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https://olympias.lib.uoi.gr/jspui/handle/123456789/14510Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Fokas, D. | en |
| dc.contributor.author | Baldino, C. M. | en |
| dc.date.accessioned | 2015-11-24T17:38:33Z | - |
| dc.date.available | 2015-11-24T17:38:33Z | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/14510 | - |
| dc.rights | Default Licence | - |
| dc.subject | diversity oriented synthesis | en |
| dc.subject | indolazonines | en |
| dc.subject | polycyclic indolic compounds | en |
| dc.subject | skeletal diversity | en |
| dc.subject | solution-phase chemistry | en |
| dc.subject | beta-tetrahydrocarbolines | en |
| dc.title | Strategies for the Synthesis of Novel Indole Alkaloid-Based Screening Libraries for Drug Discovery | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | DOI: 10.1007/s11030-005-1292-z | - |
| heal.identifier.secondary | http://www.springerlink.com/content/r25t7677j4357k61/ | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Μηχανικών Επιστήμης Υλικών | el |
| heal.publicationDate | 2005 | - |
| heal.abstract | A series of diverse indole-based chemotypes were synthesized from beta-tetrahydrocarboline (beta-THC) scaffolds prepared from commercially and readily available tryptamines and agr-ketoesters. Diversity can be generated within these chemotypes through the following strategies: (a) appendage of substituents to the beta-THC scaffold, prepared in situ or as a template, through further elaboration and (b) skeletal modifications to the beta-THC scaffold via ring forming or ring breaking reactions. The strategies described here are amenable to high throughput solution-phase parallel synthesis, providing access to novel indole-based screening libraries for drug discovery. | en |
| heal.publisher | SpringerLink | en |
| heal.journalName | Molecular Diversity | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Fokas-2005-Str.pdf | 2.06 MB | Adobe PDF | View/Open Request a copy |
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