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dc.contributor.authorGiannakeas, N.en
dc.contributor.authorFotiadis, D. I.en
dc.date.accessioned2015-11-24T17:31:26Z-
dc.date.available2015-11-24T17:31:26Z-
dc.identifier.issn0895-6111-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/13584-
dc.rightsDefault Licence-
dc.subjectmicroarray image processingen
dc.subjectgriddingen
dc.subjectsegmentationen
dc.subjectk-meansen
dc.subjectfuzzy c meansen
dc.subjectDNA microarrayen
dc.subjectgene-expressionen
dc.titleAn automated method for gridding and clustering-based segmentation of cDNA microarray imagesen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primaryDOI 10.1016/j.compmedimag.2008.10.003-
heal.identifier.secondary<Go to ISI>://000262692200006-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0895611108001018/1-s2.0-S0895611108001018-main.pdf?_tid=e492477cb5a849ab7666b7644698c4ec&acdnat=1339757179_18fa408075624e9a45cd06f474c31b88-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Μηχανικών Επιστήμης Υλικώνel
heal.publicationDate2009-
heal.abstractMicroarrays are widely used to quantify gene expression levels. Microarray image analysis is one of the tools, which are necessary when dealing with vast amounts of biological data. In this work we propose a new method for the automated analysis of microarray images. The proposed method consists of two stages: gridding and segmentation. Initially, the microarray images are preprocessed using template matching, and block and spot finding takes place. Then, the non-expressed spots are detected and a grid is fit on the image using a Voronoi diagram. In the segmentation stage, K-means and Fuzzy C means (FCM) Clustering are employed. The proposed method was evaluated using images from the Stanford Microarray Database (SMD). The results that are presented in the segmentation stage show the efficiency of our Fuzzy C means-based work compared to the two already developed K-means-based methods. The proposed method can handle images with artefacts and it is fully automated. (C) 2008 Elsevier Ltd. All rights reserved.en
heal.publisherElsevieren
heal.journalNameComputerized Medical Imaging and Graphicsen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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