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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/9981
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dc.contributor.authorXanthopoulou, M. N.en
dc.contributor.authorHadjikakou, S. K.en
dc.contributor.authorHadjiliadis, N.en
dc.contributor.authorMilaeva, E. R.en
dc.contributor.authorGracheva, J. A.en
dc.contributor.authorTyurin, V. Y.en
dc.contributor.authorKourkoumelis, N.en
dc.contributor.authorChristoforidis, K. C.en
dc.contributor.authorMetsios, A. K.en
dc.contributor.authorKarkabounas, S.en
dc.contributor.authorCharalabopoulos, K.en
dc.date.accessioned2015-11-24T16:53:10Z-
dc.date.available2015-11-24T16:53:10Z-
dc.identifier.issn0223-5234-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/9981-
dc.rightsDefault Licence-
dc.subjectbioinorganic chemistryen
dc.subjectorganotin(iv) complexesen
dc.subjects ligands-heterocyclic thioamidesen
dc.subjectcatalytic peroxidation of fatty acidsen
dc.subjectcytotoxic actionen
dc.subjectstructural-characterizationen
dc.subjectplatinum compoundsen
dc.subjectlinoleic-aciden
dc.subjectbinding-siteen
dc.subjectderivativesen
dc.subject5-chloro-2-mercaptobenzothiazoleen
dc.subjecttriethyltinen
dc.subject2-mercaptobenzothiazoleen
dc.subjectlipoxygenaseen
dc.subjectperoxidationen
dc.titleBiological studies of new organotin(IV) complexes of thioamide ligandsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primaryDOI 10.1016/j.ejmech.2007.03.028-
heal.identifier.secondary<Go to ISI>://000254031400011-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0223523407001614/1-s2.0-S0223523407001614-main.pdf?_tid=d6e4d31afbc398a09721d1bac770dc2d&acdnat=1333030315_ac546532df6fa05fba711ce1cb5a2776-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.publicationDate2008-
heal.abstractNew organotin(IV) complexes with heterocyclic thioamides 2-mercapto-benzothiazole (Hmbzt), 5-chloro-2-mercapto-benzottliazole (Hcmbzt) and 2-mercapto-benzoxazole (Hmbzo) of formulae [(C(6)H(5))(3)Sn(mbzt)] (1), [(C(6)H(5))(3)Sn(cmbzt)] (3) and [(C(6)H(5))(2)Sn(cmbzt)(2)] (4), together with the already known [(C(6)H(5))(3)Sn(mbzo)] (2), [(n-C(4)H(9))(2)Sn(cmbZt)(2)] (5) and [(CH(3))(2)Sn(cmbzt)(2)] (6) were used to study their influence on the peroxidation of oleic acid. The influence of complexes (3)-(6) upon peroxidation of oleic acid showed that the formation of reactive radicals caused the initiation of the chain radical oxidation of the substrate. The influence of complexes (1)-(6) upon the catalytic peroxidation of linoleic acid by the enzyme lipoxygenase (LOX) was also studied and compared to those of cisplatin. Compounds (1)-(6) were finally tested for in vitro cytotoxicity against leiomyosarcoma cells. (c) 2007 Elsevier Masson SAS. All rights reserved.en
heal.publisherElsevieren
heal.journalNameEur J Med Chemen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
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