Unexpected enzyme-catalyzed regioselective acylation of flavonoid aglycones and rapid product screening (Journal article)

Kyriakou, E./ Primikyri, A./ Charisiadis, P./ Katsoura, M./ Gerothanassis, I. P./ Stamatis, H./ Tzakos, A. G.


Unprecedented regioselective acylation of flavonoid aglycones was achieved using Candida antarctica lipase B (CALB). The rapid screening of product formation was performed by the use of the high resolution phenol-type OH H-1 NMR spectral region recorded after the addition of picric acid.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας
Keywords: human leukemia-cells,candida-antarctica,quercetin acetylation,natural-products,lipase,derivatives,inhibitors,insights,media,death
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/9805
ISSN: 1477-0520
Link: <Go to ISI>://000300047600005
http://pubs.rsc.org/en/Content/ArticleLanding/2012/OB/c2ob06784f
Publisher: Royal Society of Chemistry
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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