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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/8336
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dc.contributor.authorTentolouris, N.en
dc.contributor.authorKolia, M.en
dc.contributor.authorTselepis, A. D.en
dc.contributor.authorPerea, D.en
dc.contributor.authorKitsou, E.en
dc.contributor.authorKyriaki, D.en
dc.contributor.authorTambaki, A. P.en
dc.contributor.authorKarabina, S. P.en
dc.contributor.authorSala, C.en
dc.contributor.authorFragoulopoulos, E.en
dc.contributor.authorKatsilambros, N.en
dc.date.accessioned2015-11-24T16:40:56Z-
dc.date.available2015-11-24T16:40:56Z-
dc.identifier.issn0947-7349-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/8336-
dc.rightsDefault Licence-
dc.subjectrepaglinideen
dc.subjecttype 2 diabetes mellitusen
dc.subjecttriglyceridesen
dc.subjectpostprandial triglyceridaemiaen
dc.subjectlipoprotein subfractionsen
dc.subjecttriglycerideen
dc.subjectmetabolismen
dc.subjectniddmen
dc.titleLack of effect of acute repaglinide administration on postprandial lipaemia in patients with type 2 diabetes mellitusen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondary<Go to ISI>://000185875000012-
heal.identifier.secondaryhttps://www.thieme-connect.de/DOI/DOI?10.1055/s-2003-42729-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.publicationDate2003-
heal.abstractThe effect of acute repaglinide administration (2 mg) on postprandial glycaemia and lipaemia has been examined in 20 subjects with type 2 diabetes mellitus. Each subject received in the morning, after a 12 to 14 h fast, a standard mixed meal (total energy 783 kcal), preceded by one tablet of 2 mg repaglinide or placebo. Chylomicrons and chylomicron-deficient plasma were prepared by ultracentrifugation. Triglyceride levels in CM fraction (CM-triglycerides) in total plasma as well as in CM-deficient plasma (non-CM-triglycerides) were determined. A significant reduction in postprandial glycaemia was observed after repaglinide administration compared to placebo (p < 0.001). Plasma concentrations of total triglycerides, CM-triglycerides, non-CM-triglycerides, free fatty acids and the other plasma lipids measured, were not significantly different between the two phases of the study. It is concluded that, in contrast to sulphonylureas, acute repaglinide administration does not improve postprandial lipaemia in patients with type 2 diabetes.en
heal.journalNameExperimental and Clinical Endocrinology & Diabetesen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
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