1. Repository of OAI
  2. ΑΠΟΘΕΤΗΡΙΟ "ΟΛΥΜΠΙΑΣ"
  3. Σχολή Επιστημών Υγείας
  4. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιών
  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)
Ελληνικά   English  
Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/7565
Full metadata record
DC FieldValueLanguage
dc.contributor.authorIoannidis, P.en
dc.contributor.authorTrangas, T.en
dc.contributor.authorDimitriadis, E.en
dc.contributor.authorSamiotaki, M.en
dc.contributor.authorKyriazoglou, I.en
dc.contributor.authorTsiapalis, C. M.en
dc.contributor.authorKittas, C.en
dc.contributor.authorAgnantis, N.en
dc.contributor.authorNielsen, F. C.en
dc.contributor.authorNielsen, J.en
dc.contributor.authorChristiansen, J.en
dc.contributor.authorPandis, N.en
dc.date.accessioned2015-11-24T16:32:34Z-
dc.date.available2015-11-24T16:32:34Z-
dc.identifier.issn0020-7136-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/7565-
dc.rightsDefault Licence-
dc.subjectAmino Acid Motifsen
dc.subjectAnimalsen
dc.subjectBase Sequenceen
dc.subjectCell Divisionen
dc.subjectChromosome Mappingen
dc.subjectDNA, Complementary/metabolismen
dc.subjectHumansen
dc.subjectMesenchymoma/*metabolismen
dc.subjectMiceen
dc.subjectMolecular Sequence Dataen
dc.subjectProtein Bindingen
dc.subjectProto-Oncogene Proteins c-myc/metabolismen
dc.subjectRNA/metabolismen
dc.subjectRNA,en
dc.titleC-MYC and IGF-II mRNA-binding protein (CRD-BP/IMP-1) in benign and malignant mesenchymal tumorsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11745432-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιώνel
heal.publicationDate2001-
heal.abstractMouse coding region determinant-binding (mCRD-BP) and human IGF-II mRNA-binding 1 (hIMP-1) proteins are orthologous mRNA-binding proteins that recognize c-myc and IGF-II mRNA, respectively, and regulate their expression posttranscriptionally. Here, we confirm that human CRD-BP/IMP-1 binds to c-myc mRNA and that it is predominantly expressed in fetal tissues. Moreover, hCRD-BP/IMP-1 expression was detected in cell lines of neoplastic origin and in selected primary tumors. In a series of 33 malignant and 10 benign mesenchymal tumors, 73% and 40%, respectively, were found to express hCRD-BP/IMP-1. In particular, expression was significant in 14 Ewing's sarcomas, all of which were positive. The data suggest that hCRD-BP/IMP-1 plays a role in abnormal cell proliferation in mesenchymal tumors.en
heal.journalNameInt J Canceren
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

Show simple item record
Files in This Item:
There are no files associated with this item.
Show simple item record  


This item is licensed under a Creative Commons License Creative Commons