Disability complications in inflammatory bowel disease patient in Northwest Greece (Doctoral thesis)

Μαντζουράνης, Γεώργιος


Introduction: Sexual dysfunction and restorative surgical operations in IBD patients are debilitating complications of the disease. In IBD patients, the surgical approach may be considered only after all the other means of treatment have failed, in order for the disease to be manageable; sexual dysfunction, on the other hand, may be due to psychological or biological factors. Aim: The aim of the present study was to examine all the data regarding IBD patients who were being monitored and were diagnosed with ileus and were treated surgically or not. We also reviewed the literature on the incidence of sexual dysfunction in IBD patients. Methods: Sexual dysfunction was investigated via a systematic literature review, given that there was no standardized and valid instrument for a quantitative study to take place. The retrospective quantitative study took place in patients monitored at the Gastroenterology Dept. of the University Hospital of Ioannina, Greece, and the ‘Hadzikostas’ General Hospital of Ioannina, between 1982-2015 and had been diagnosed with ileus (n= 37). Results: Sexual dysfunction may aggravate IBD patients' quality of life, thus it may qualify as a debilitating side-effect. Being a chronic condition followed by continual relapses, it may be exhausting for the patients and have an impact on their quality of sexual life, and their general quality of life overall. Regarding surgical operations, 66.7% of the patients diagnosed with Crohn's Disease (CD) were males, and 33.3% females. The average age of CD patients was 50.4 (20.9) years, the youngest being 27 and the oldest 86 years old, while the average age of ulcerative colitis (UC) patients was 66.8 (17.7), the youngest being 28 and the oldest 86. From our sample, 56.3% of the UC patients were men and 43.8% women. 33.3% of the patients with CD and 43.8% of those with UC had full-blown ileus which was investigated with endoscopy or surgical operation, one patient had subileus, and one toxic megacolon. From our sample, 88.4% of the patients had had no extra-intestinal surgical operations prior to the diagnosis, while 92.8% of them had had no intestinal operations at all. Moreover, 97.1% of the patients had had no extra-intestinal operations after the diagnosis, and 96.7% of them had had no intestinal operations at all. Regarding other surgical operations of the participating patients, 85.7% of CD patients had had no previous operation on the abdomen, compared to 93.8% of the UC patients. From those suffering from CD, 9.5% were submitted to endoscopy and surgery, compared to 12.5% of UC patients who had had endoscopy and then surgery. 4.8% of the CD patients had had a CT scan after the endoscopy, while 6.3% of the UC patients had had the CT scan before the endoscopy and 6.3% after it. In total, 28.6% of CD patients and 37.5% of UC patients were submitted to CT scan. Also, 23.8% of CD patients and 37.5% of UC patients were submitted to surgery. Conclusions: Sexual dysfunction and surgical operations qualify as debilitating side-effects. More investigation and interdisciplinary management is needed.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Subject classification: Φλεγμονώδεις νόσοι του εντέρου
Keywords: Ιδιοπαθείς φλεγμονώδεις νόσοι εντέρου,Σεξουαλική δυσλειτουργία,Αναπηρικές επιπλοκές,Ελκώδης κολίτιδα,Νόσος chron,Inflammatory bowel diseases,Sexual dysfunction,Disability complications,Ulcerative colitis,Crohn's diseas
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/29467
Appears in Collections:Διδακτορικές Διατριβές

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