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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Arvanitis, D. L. | en |
| dc.contributor.author | Kamper, E. F. | en |
| dc.contributor.author | Kopeikina, L. | en |
| dc.contributor.author | Stavridou, A. | en |
| dc.contributor.author | Sgantzos, M. N. | en |
| dc.contributor.author | Kallioras, V. | en |
| dc.contributor.author | Athanasiou, E. | en |
| dc.contributor.author | Kanavaros, P. | en |
| dc.date.accessioned | 2015-11-24T19:42:41Z | - |
| dc.date.available | 2015-11-24T19:42:41Z | - |
| dc.identifier.issn | 0213-3911 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24678 | - |
| dc.rights | Default Licence | - |
| dc.subject | Adenocarcinoma/*metabolism/pathology | en |
| dc.subject | Adenocarcinoma, Mucinous/*metabolism/pathology | en |
| dc.subject | Blood Proteins/*biosynthesis | en |
| dc.subject | Carcinoma, Signet Ring Cell/*metabolism/pathology | en |
| dc.subject | Humans | en |
| dc.subject | *Lectins, C-Type | en |
| dc.subject | Stomach/*metabolism/pathology | en |
| dc.subject | Stomach Neoplasms/*metabolism/pathology | en |
| dc.title | Tetranectin expression in gastric adenocarcinomas | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/11962752 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2002 | - |
| heal.abstract | AIMS: The aim was to analyze the immunohistochemical localization of tetranectin in gastric adenocarcinomas and the adjacent tissues of the wall of the stomach. METHODS AND RESULTS: Forty cases of gastric adenocarcinomas were stained by the indirect immunoperoxidase method. Of the ten cases of mucinous signet ring cell carcinomas 5 showed high, 3 moderate and 2 low tetranectin expression. Of the ten cases of well-differentiated intestinal type adenocarcinomas (ITA) 4 showed moderate regional, 3 low regional and 3 negative tetranectin expression. Of the ten cases of moderately-differentiated ITA 3 showed moderate regional, 4 low regional and 3 negative tetranectin expression. Of the ten cases of poorly-differentiated ITA 4 showed focal low and 6 negative tetranectin expression. Overall, the mucinous signet ring carcinomas showed significantly higher tetranectin expression compared to ITA (chi2 = 3.95, p<0.05). In contrast, no significant relationship was found between tetranectin expression and the degree of differentiation in ITA (chi2 = 2.5, p>0.05). In all cases, the perineoplastic desmoplastic reactive stroma showed high expression of tetranectin intra- and extracellularly. The mast cells and goblet cells in the areas of intestinal metaplasia showed high tetranectin expression. CONCLUSIONS: This study shows that: a) tetranectin is produced and deposited extracellularly in the desmoplastic peritumoral stroma of infiltrating gastric adenocarcinomas; b) tetranectin is more highly expressed by the mucinous signet ring cell carcinomas compared to ITA; and c) the amount of tetranectin produced by the ITA is unrelated with the degree of tumor differentiation. | en |
| heal.journalName | Histol Histopathol | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Kanavaros-2002-tetranectin expression in.pdf | 91.56 kB | Adobe PDF | View/Open Request a copy |
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