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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/24670
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dc.contributor.authorVairaktaris, E.en
dc.contributor.authorYapijakis, C.en
dc.contributor.authorNkenke, E.en
dc.contributor.authorVassiliou, S.en
dc.contributor.authorVylliotis, A.en
dc.contributor.authorNixon, A. M.en
dc.contributor.authorDerka, S.en
dc.contributor.authorRagos, V.en
dc.contributor.authorSpyridonidou, S.en
dc.contributor.authorTsigris, C.en
dc.contributor.authorNeukam, F. W.en
dc.contributor.authorPatsouris, E.en
dc.date.accessioned2015-11-24T19:42:38Z-
dc.date.available2015-11-24T19:42:38Z-
dc.identifier.issn0361-8609-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24670-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectCarboxypeptidase U/*geneticsen
dc.subjectCarcinoma, Squamous Cell/*geneticsen
dc.subjectCase-Control Studiesen
dc.subjectFemaleen
dc.subjectGene Frequencyen
dc.subject*Genetic Predisposition to Diseaseen
dc.subjectGermanyen
dc.subjectGreeceen
dc.subjectHomozygoteen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMouth Neoplasms/*geneticsen
dc.subjectPolymorphism, Single Nucleotide/*geneticsen
dc.titleThe 1040C/T polymorphism influencing thermal stability and activity of thrombin activatable fibrinolysis inhibitor is associated with risk for oral canceren
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1002/ajh.20985-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/17636471-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1002/ajh.20985/asset/20985_ftp.pdf?v=1&t=h0atvxln&s=71caa113aec971d022dddc814abf1874ce031163-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2007-
heal.abstractNo studies thus far have investigated the contribution of thrombin activatable fibrinolysis inhibitor (TAFI) to oral oncogenesis. We studied the activity-related 1040C/T polymorphism in 150 patients with oral cancer and 138 healthy controls matched by age, gender, and ethnicity. The increased-activity T allele frequency was significantly reduced in patients compared with controls (28.7% vs. 37.0%, P < 0.05). T/T homozygotes had about half the probability of developing oral cancer (O.R. 0.39, 95%C.I. 0.13-1.14), while no significant difference was observed in C/T heterozygotes. The observed prophylactic effect of increased TAFI activity might result from reduction of plasmin and inhibition of extracellular matrix dissolution.en
heal.journalNameAm J Hematolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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