Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/24623
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dc.contributor.authorChristou, G. A.en
dc.contributor.authorTellis, C. C.en
dc.contributor.authorElisaf, M. S.en
dc.contributor.authorTselepis, A. D.en
dc.contributor.authorKiortsis, D. N.en
dc.date.accessioned2015-11-24T19:42:19Z-
dc.date.available2015-11-24T19:42:19Z-
dc.identifier.issn1940-1574-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24623-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectApolipoproteins B/*blooden
dc.subjectCaloric Restrictionen
dc.subjectDiet, Fat-Restricteden
dc.subjectFemaleen
dc.subjectFenofibrate/therapeutic useen
dc.subjectHumansen
dc.subjectHypertriglyceridemia/*blood/etiology/*therapyen
dc.subjectHypolipidemic Agents/therapeutic useen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectObesity/*blood/complications/*therapyen
dc.subjectPiperidines/therapeutic useen
dc.subjectPyrazoles/therapeutic useen
dc.subjectRetinol-Binding Proteins, Plasma/*metabolismen
dc.titleThe changes in plasma retinol-binding protein 4 levels are associated with those of the apolipoprotein B-containing lipoproteins during dietary and drug treatmenten
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1177/0003319711407628-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/21602259-
heal.identifier.secondaryhttp://ang.sagepub.com/content/63/1/67.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2012-
heal.abstractWe investigated the association between retinol-binding protein 4 (RBP(4)) and apolipoprotein B (ApoB)-containing lipoproteins. Obese or overweight, hypertriglyceridemic patients underwent the following interventions for 3 months: (1) Diet (n = 20), (2) Diet + fenofibrate (n = 18), (3) Diet + rimonabant (n = 8). Circulating RBP4 decreased during dietary treatment. The percentage change in RBP(4) was positively correlated with the percentage changes in very-low density lipoprotein cholesterol (r = .570, P = .02), low-density lipoprotein cholesterol ([LDL-C]; r = .605, P = .01), ApoB (r = .705, P = .007), and small dense LDL-C ([sdLDL-C]; r = .872, P < .001). The percentage change in RBP4 was the best predictor of the percentage changes in sdLDL-C and ApoB. Rimonabant treatment reduced RBP4, whereas fenofibrate increased RBP4 during the first month of therapy followed by a subsequent decrease. In conclusion, RBP4 may significantly influence the metabolic pathways responsible for changes in ApoB lipoprotein subspecies, thus RBP4 may be associated with cardiovascular disease risk.en
heal.journalNameAngiologyen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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