Vitrectomy results for diffuse diabetic macular edema with and without inner limiting membrane removal (Journal article)

Stefaniotou, M./ Aspiotis, M./ Kalogeropoulos, C./ Christodoulou, A./ Psylla, M./ Ioachim, E./ Alamanos, I./ Psilas, K.

PURPOSE: To determine whether vitrectomy for diffuse diabetic macular edema with and without internal limiting membrane (ILM) peeling is equally effective in reducing edema. METHODS: The authors retrospectively analyzed the surgical outcomes in 73 eyes of 52 patients with diffuse diabetic macular edema. Eighteen eyes (Group A) underwent three-port pars plana vitrectomy with posterior hyaloid membrane (PHM) removal, while 55 eyes (Group B) had pars plana vitrectomy with additional ILM peeling after PHM removal. RESULTS: Intraoperatively, the posterior hyaloid was found to be attached to the macula in all eyes. In Group A, macular edema resolved completely in 8 eyes (44.4%) with improvement of visual acuity (VA). In Group B, VA improved in 38 eyes (69.1%) with complete resolution of edema. The results of this study indicated that vitrectomy effectively reduced macular edema but eyes with ILM peeling (Group B) presented better results than those without ILM peeling. Another important factor related to the outcome seems to be the level of glycosylated hemoglobin (HbA1c). CONCLUSIONS: In eyes with diffuse diabetic macular edema vitrectomy seems to be effective, but additional ILM peeling presented better results.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Aged,Basement Membrane/pathology/*surgery/ultrastructure,Diabetic Retinopathy/pathology/*surgery,Female,Fluorescein Angiography,Fundus Oculi,Humans,Macular Edema/pathology/*surgery,Male,Middle Aged,Postoperative Complications,Retrospective Studies,Treatment Outcome,Visual Acuity,Vitrectomy/*methods
URI: https://olympias.lib.uoi.gr/jspui/handle/123456789/24386
ISSN: 1120-6721
Link: http://www.ncbi.nlm.nih.gov/pubmed/15134111
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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