A rare case of primary malignant melanoma of the scrotum diagnosed by fine-needle aspiration (Journal article)

Damala, K./ Tsanou, E./ Pappa, L./ Sintou-Mantela, E./ Peschos, D./ Agnantis, N. J./ Malamou-Mitsi, V.


We report a case of a 55-yr-old man with malignant melanoma of scrotum. He was referred to our Hospital with a complaint of gradual focal enlargement of the scrotum in a period of 3 yr. On physical examination, a pigmented, poorly marginated mass, with central necrosis was observed. A fine-needle aspiration (FNA) of the lesion was performed. Cytological examination revealed highly cellular smears, containing malignant cells, dispersed or arranged in loose aggregates. Cellular morphology and characteristics were identical to those of malignant melanoma arising elsewhere in the skin. The immunocytochemical study revealed positivity of neoplastic cells for anti-melanoma monoclonal antibody (HMB-45) antigen. Histological confirmation finally was provided after wide excision of the lesion. We emphasize the difficulties in differential diagnosis considerations and diagnostic pitfalls of scrotal lesions.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Biopsy, Fine-Needle,Genital Neoplasms, Male/*pathology,Humans,Male,Melanoma/*pathology,Middle Aged,Scrotum/*pathology
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/24237
ISSN: 8755-1039
Link: http://www.ncbi.nlm.nih.gov/pubmed/15540172
http://onlinelibrary.wiley.com/store/10.1002/dc.20153/asset/20153_ftp.pdf?v=1&t=h0ezys1w&s=469e7e52ced62e86c0478a97d1241d51d0d528f6
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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