Acid-base and electrolyte abnormalities in febrile patients with bacteraemia (Journal article)

Elisaf, M. S./ Theodorou, J./ Pappas, H./ Siamopoulos, K. C.

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dc.contributor.authorElisaf, M. S.en
dc.contributor.authorTheodorou, J.en
dc.contributor.authorPappas, H.en
dc.contributor.authorSiamopoulos, K. C.en
dc.date.accessioned2015-11-24T19:38:21Z-
dc.date.available2015-11-24T19:38:21Z-
dc.identifier.issn1165-0478-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24140-
dc.rightsDefault Licence-
dc.subjectAcid-Base Imbalance/*etiologyen
dc.subjectAcidosis/etiologyen
dc.subjectAdulten
dc.subjectAlkalosis/etiologyen
dc.subjectBacteremia/*complicationsen
dc.subjectFever/*etiologyen
dc.subjectGram-Negative Bacterial Infections/complicationsen
dc.subjectHumansen
dc.subjectHypocalcemia/etiologyen
dc.subjectHypokalemia/etiologyen
dc.subjectHypophosphatemia/etiologyen
dc.subjectMagnesium/blooden
dc.subjectMiddle Ageden
dc.subjectWater-Electrolyte Imbalance/*etiologyen
dc.titleAcid-base and electrolyte abnormalities in febrile patients with bacteraemiaen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/8258028-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1993-
heal.abstractOBJECTIVES: Very commonly febrile patients with bacteraemia develop a variety of acid-base and electrolyte disturbances which play a significant role in the morbidity and mortality of these patients. This study was undertaken to describe the pathogenetic mechanisms of these abnormalities in febrile patients with bacteraemia. METHODS: Fifteen febrile patients with bacteraemia, aged 24-62 years, were studied. In all patients blood cultures revealed Gram-negative rods. None of them had septic shock, diabetes mellitus, renal or liver failure and none was receiving drugs influencing acid-base balance and electrolyte levels or was a heavy alcohol consumer. RESULTS: Nine patients had respiratory alkalosis, which was possibly due to bacterial toxins, while the remaining 6 had a wide-gap metabolic (lactic) acidosis coexisting with respiratory alkalosis. Hypokalaemia was found in four patients and was mainly due to respiratory alkalosis. However, kaliuria due to hypomagnesaemia contributed to hypokalaemia in 2 patients. Hypomagnesaemia was detected in 3 patients and was attributed to respiratory alkalosis as well as to magnesiuria induced by metabolic acidosis or phosphate depletion. Hypophosphataemia was found in 5 patients who also had respiratory alkalosis and/or phosphaturia due to metabolic acidosis or hypomagnesaemia. Finally, one patient had multifactorial origin hypocalcaemia. CONCLUSION: Febrile patients with bacteraemia develop a number of acid-base and electrolyte disturbances attributed to various pathogenetic mechanisms.en
heal.journalNameEur J Meden
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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