The natural course of primary Sjogren's syndrome (a clinical study) (Journal article)

Pavlidis, N. A./ Drosos, A. A./ Galanopoulos, V./ Siamopoulos, C./ Tsianos, E. B.


In this work the authors analyzed the clinical course and diagnostic procedures of 104 patients with primary Sjogren's syndrome (pSS): 57 patients diagnosed and followed-up at Ioannina University and 47 similar patients treated at the National Institute of Health (USA). Both studies have shown that pSS is predominantly a female disease with a latent period of 6-8 yrs from the time of the first symptom to the time of final diagnosis. Although the syndrome begins almost exclusively with glandular manifestations (xerostomia, xerophthalmia or parotid gland enlargement), in a respectable percentage of patients it eventually progresses to extraglandular involvement. pSS can be potentially complicated by benign (pseudolymphoma) or malignant (lymphoma) lymphoproliferative disorders.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Adult,Female,Greece,Humans,Hypertrophy,Lymphoma/etiology,Middle Aged,Parotid Gland/pathology,Raynaud Disease/diagnosis,Sjogren's Syndrome/complications/diagnosis/*ethnology,United States,Xerophthalmia/diagnosis/ethnology,Xerostomia/diagnosis/ethnology
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/23931
ISSN: 0040-3660
Link: http://www.ncbi.nlm.nih.gov/pubmed/3394101
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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