Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23801
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dc.contributor.authorManoussakis, M. N.en
dc.contributor.authorGharavi, A. E.en
dc.contributor.authorDrosos, A. A.en
dc.contributor.authorKitridou, R. C.en
dc.contributor.authorMoutsopoulos, H. M.en
dc.date.accessioned2015-11-24T19:36:04Z-
dc.date.available2015-11-24T19:36:04Z-
dc.identifier.issn0090-1229-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23801-
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectAutoantibodies/*analysis/immunologyen
dc.subjectAutoimmune Diseases/*immunologyen
dc.subjectCardiolipins/*immunologyen
dc.subjectEnzyme-Linked Immunosorbent Assayen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectImmunoglobulin G/analysisen
dc.subjectImmunoglobulin M/analysisen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectRheumatic Diseases/*immunologyen
dc.subjectThromboembolism/*immunologyen
dc.titleAnticardiolipin antibodies in unselected autoimmune rheumatic disease patientsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/3497746-
heal.identifier.secondaryhttp://ac.els-cdn.com/0090122987900730/1-s2.0-0090122987900730-main.pdf?_tid=7a55ad966616f2ac11874dacb2d2daaa&acdnat=1333524872_e3f75cf44de4bd97282ffd4a6244c16e-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1987-
heal.abstractQuantitative determination of IgG and IgM antibodies to cardiolipin (anti-CL) was performed with a newly developed sensitive and specific ELISA method. We studied a cohort of 361 unselected patients with various autoimmune rheumatic diseases (ARD), 69 patients with thromboembolic phenomena (TEP) unassociated with ARD, and 267 healthy blood donors (HBD). Anti-CL of at least one immunoglobulin class were found in 42 (11.6%) of the ARD patients, in 3 (4.3%) of the TEP patients (2 with myocardial infarction and 1 with pulmonary emboli), and in 6 (2.3%) of the HBD. In ARD patients anti-CL were more prevalent in patients with systemic lupus erythematosus (SLE) and overlap syndromes. Significant correlations included CNS involvement (particularly seizures) and features of immune hyperreactivity (splenomegaly-lymphadenopathy, ANA, and antibodies to Ro(SSA), U1-nRNP, and double-stranded DNA). No statistical correlation could be demonstrated between the presence of anti-CL and thrombotic events, hematologic disorders, or recurrent abortions in the ARD patients.en
heal.journalNameClin Immunol Immunopatholen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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