Anti-Ro(SSA) positive rheumatoid arthritis (RA): a clinicoserological group of patients with high incidence of D-penicillamine side effects (Journal article)

Moutsopoulos, H. M./ Skopouli, F. N./ Sarras, A. K./ Tsampoulas, C./ Mavridis, A. K./ Constantopoulos, S. H./ Maddison, P. J.


The clinical, laboratory, histological, and radiological manifestations of 90 Greek patients with anti-Ro(SSA) negative rheumatoid arthritis (RA) were compared with those of 15 Greek patients with anti-Ro(SSA) positive RA. Anti-Ro(SSA) positive RA patients had the same articular and extra-articular manifestations as anti-Ro(SSA) negative patients. However, they were predominantly females with lower rheumatoid factor titres and a high incidence of positive minor salivary gland biopsy specimens for Sjogren's syndrome. Finally, anti-Ro(SSA) positive RA patients frequently experienced penicillamine side effects.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Adult,Antibodies, Antinuclear/*analysis,Arthritis, Rheumatoid/complications/drug therapy/*immunology,Female,Humans,Male,Middle Aged,Penicillamine/adverse effects
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/23767
ISSN: 0003-4967
Link: http://www.ncbi.nlm.nih.gov/pubmed/3872635
http://ard.bmj.com/content/44/4/215.full.pdf
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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