Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23754
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dc.contributor.authorJohnson, E. O.en
dc.contributor.authorKonstandi, M.en
dc.contributor.authorBabis, G. C.en
dc.contributor.authorPiagkou, M.en
dc.contributor.authorSoucacos, P. N.en
dc.date.accessioned2015-11-24T19:35:49Z-
dc.date.available2015-11-24T19:35:49Z-
dc.identifier.issn1875-6212-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23754-
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectAnticoagulants/*pharmacology/*therapeutic useen
dc.subjectBlood Coagulation/*drug effectsen
dc.subjectClinical Trials as Topicen
dc.subjectFibrinolytic Agents/pharmacology/therapeutic useen
dc.subjectHumansen
dc.subjectLower Extremity/*surgeryen
dc.subjectOrthopedic Procedures/*adverse effects/methodsen
dc.subjectVenous Thromboembolism/*blood/*prevention & controlen
dc.titleThe plasma coagulation cascade: potential targets for novel anticoagulants in major lower limb surgeryen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/21044025-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2011-
heal.abstractStrategies for prevention of venous thromboembolism in orthopaedic patients undergoing major lower limb surgery include pharmacological prophylaxis. Over the last three decades, the search for new safe and effective approaches for the prevention of venous thromboembolism in these patients has continued. Increased understanding of the haemostatic process has led to a clearer appreciation of the mechanisms of action of antithrombotic drugs already in use as well as the identification of new targets for novel drug development. As a result, the development of new anticoagulants has advanced rapidly over recent years. The molecular targets of several novel anticoagulants, and their effectiveness in early Phase II and Phase III trials are reviewed.en
heal.journalNameCurr Vasc Pharmacolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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