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  4. Τμήμα Ιατρικής
  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23621
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dc.contributor.authorMathioudaki, K.en
dc.contributor.authorPapadokostopoulou, A.en
dc.contributor.authorScorilas, A.en
dc.contributor.authorXynopoulos, D.en
dc.contributor.authorAgnanti, N.en
dc.contributor.authorTalieri, M.en
dc.date.accessioned2015-11-24T19:34:26Z-
dc.date.available2015-11-24T19:34:26Z-
dc.identifier.issn1532-1827-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23621-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectBiopsyen
dc.subjectColonic Neoplasms/*enzymology/*genetics/pathology/surgeryen
dc.subjectDNA, Complementary/geneticsen
dc.subjectDisease Progressionen
dc.subjectGene Expression Regulation, Neoplastic/*geneticsen
dc.subjectHumansen
dc.subjectMiddle Ageden
dc.subjectPrognosisen
dc.subjectProtein-Arginine N-Methyltransferases/*genetics/metabolismen
dc.subjectRepressor Proteins/*genetics/metabolismen
dc.titleThe PRMT1 gene expression pattern in colon canceren
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1038/sj.bjc.6604807-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/19078953-
heal.identifier.secondaryhttp://www.nature.com/bjc/journal/v99/n12/pdf/6604807a.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2008-
heal.abstractThe methylation of arginine has been implicated in many cellular processes, such as regulation of transcription, mRNA splicing, RNA metabolism and transport. The enzymes responsible for this modification are the protein arginine methyltransferases. The most abundant methyltransferase in human cells is protein arginine methyltransferase 1. Methylation processes appear to interfere in the emergence of several diseases, including cancer. During our study, we examined the expression pattern of protein arginine methyltransferase 1 gene in colon cancer patients. The emerging results showed that the expression of one of the gene variants is associated with statistical significant probability to clinical and histological parameters, such as nodal status and stage. This is a first attempt to acquire an insight on the possible relation of the expression pattern of protein arginine methyltransferase 1 and colon cancer progression.en
heal.journalNameBr J Canceren
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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