Blood pressure drug therapy and electrolyte disturbances (Journal article)

Liamis, G./ Milionis, H./ Elisaf, M. S.


Antihypertensive pharmacologic treatment may be associated with diverse disturbances of electrolyte homeostasis. These drug-induced disorders are relatively common, typically including hyponatraemia, hypokalaemia, hyperkalaemia, hypomagnesaemia, hypophosphataemia and hypercalcaemia. Diuretics, beta-blockers, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are particularly likely to cause these complications. Recognised risk factors include high-dosage regimens (especially diuretics), old age, diabetes and impairment of renal function. Strategies to prevent these adverse drug reactions involve careful consideration of risk factors and clinical and laboratory evaluation in the course of treatment.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Antihypertensive Agents/*adverse effects,Blood Pressure/*drug effects,Humans,Hypertension/*drug therapy,Water-Electrolyte Imbalance/*chemically induced
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/23445
ISSN: 1742-1241
Link: http://www.ncbi.nlm.nih.gov/pubmed/18822027
http://onlinelibrary.wiley.com/store/10.1111/j.1742-1241.2008.01860.x/asset/j.1742-1241.2008.01860.x.pdf?v=1&t=h0tcjxs3&s=d31bd1650762004dd9e4963c02d8229259a0f6be
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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