The role of cadherin/catenin complex in malignant melanoma (Journal article)

Bonitsis, N./ Batistatou, A./ Karantima, S./ Charalabopoulos, K.


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dc.contributor.authorBonitsis, N.en
dc.contributor.authorBatistatou, A.en
dc.contributor.authorKarantima, S.en
dc.contributor.authorCharalabopoulos, K.en
dc.date.accessioned2015-11-24T19:31:42Z-
dc.date.available2015-11-24T19:31:42Z-
dc.identifier.issn1812-9269-
dc.identifier.urihttp://olympias.lib.uoi.gr/jspui/handle/123456789/23309-
dc.rightsDefault Licence-
dc.subjectCadherins/analysis/*metabolismen
dc.subjectCatenins/analysis/*metabolismen
dc.subjectHumansen
dc.subjectMelanoma/metabolism/*pathologyen
dc.subjectSkin Neoplasms/metabolism/*pathologyen
dc.titleThe role of cadherin/catenin complex in malignant melanomaen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/17080010-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2006-
heal.abstractIn the present review article the role of cadherin/catenin complex in cases of malignant melanoma is discussed in some detail. Cadherins represent the most important superfamily of adhesion molecules with epithelial E-cadherin being the most studied. Its role in normal state as well as in cancer invasion and metastasis and some other pathologies is crucial. E-cadherin expression is altered in malignant melanomas and its downregulation or absence is associated with melanoma invasion and metastasis potential. A shift from E-cadherin expression to neural N-cadherin expression in melanocytes is also detected in malignant melanomas formation. In addition, a discussion regarding the role of placental P-cadherin and vascular endothelial VE-cadherin as well as the recently identified molecule of dysadherin, is attempted in brief.en
heal.journalNameExp Oncolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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