Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23105
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dc.contributor.authorGiannakakis, I. A.en
dc.contributor.authorHaidich, A. B.en
dc.contributor.authorContopoulos-Ioannidis, D. G.en
dc.contributor.authorPapanikolaou, G. N.en
dc.contributor.authorBaltogianni, M. S.en
dc.contributor.authorIoannidis, J. P.en
dc.date.accessioned2015-11-24T19:30:29Z-
dc.date.available2015-11-24T19:30:29Z-
dc.identifier.issn0895-4356-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23105-
dc.rightsDefault Licence-
dc.subjectAnalysis of Varianceen
dc.subject*Evidence-Based Medicine/standards/statistics & numerical data/trendsen
dc.subjectGreat Britainen
dc.subjectHumansen
dc.subjectPeer Reviewen
dc.subjectPractice Guidelines as Topic/*standardsen
dc.subjectPreventive Medicine/*standardsen
dc.subject*Publication Biasen
dc.subjectPublishing/standardsen
dc.subjectQuality Controlen
dc.subject*Randomized Controlled Trials as Topic/standards/statistics & numericalen
dc.subjectdata/trendsen
dc.subjectResearch Designen
dc.subjectTherapeutics/*standardsen
dc.subjectTime Factorsen
dc.subjectUnited Statesen
dc.titleCitation of randomized evidence in support of guidelines of therapeutic and preventive interventionsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/12063096-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2002-
heal.abstractGuideline statements may be supported by evidence obtained from various study designs, but randomized trials are usually considered most important for making recommendations about therapeutic and preventive interventions. This study evaluated the extent to which randomized trials are cited in guidelines published in major journals. The references of 191 guidelines of therapeutic and/or preventive interventions published in Annals of Internal Medicine, BMJ, JAMA, Lancet, NEJM and Pediatrics in 1979, 1984, 1989, 1994, and 1999, were analyzed. The percentage of guidelines not citing any randomized controlled trials (RCTs) decreased gradually from 95% in 1979 to 53% in 1999. Among 4,853 references of the guidelines, there were 393 RCTs (8.1% of total), 19 systematic reviews (0.4%), and 23 meta-analyses of RCTs (0.5%). Among 19 guidelines published in 1999 or 1994 with <2 RCTs cited, in eight cases additional pertinent RCTs were identified that had not been cited by the guideline. There is a clear increase in the use of randomized evidence by guidelines over time. However, several guidelines in major journals still cite few or no RCTs.en
heal.journalNameJ Clin Epidemiolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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