Clinical characteristics and follow-up of patients with chest pain and normal coronary arteries (Journal article)

Foussas, S. G./ Adamopoulou, E. N./ Kafaltis, N. A./ Fakiolas, C./ Olympios, C./ Pisimissis, E./ Siogas, K./ Pappas, S./ Cokkinos, D. V./ Sideris, D.

The authors identified 160 men and women from all 3,700 patients with anginal pain between 1990 and 1994 who were subsequently found to have normal coronary arteries at diagnostic cardiac catheterization with follow-up to the present (mean follow-up 2.5 years). The group comprised 50 women and 110 men. Mean age was significantly greater in women (53.1 +/- 7.7 vs 47.2 +/- 9.2 years, p<0.001). Forty percent of the women but only 10% of the men had a positive exercise test. At follow-up, a larger proportion of patients continue to experience chest pain (95 patients, 59%) of whom 65 patients (41%) continue antianginal therapy. Furthermore one patient suffered a sudden cardiac death and two patients had a nonfatal myocardial infarction. Of patients referred with chest pain, women were more likely to have normal coronary arteries, compared with men. All patients have an excellent prognosis. A large proportion of women had a positive exercise test in the absence of coronary artery disease. On the other hand, morbidity remains high in these patients, despite the reassurance of a normal-appearing coronary arteriogram.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Activities of Daily Living,Age Factors,Angina Pectoris/drug therapy/physiopathology,Coronary Angiography,Coronary Vessels/anatomy & histology,Death, Sudden, Cardiac/etiology,Exercise Test,Female,Follow-Up Studies,Heart Catheterization,Humans,Longitudinal Studies,Male,Microvascular Angina/complications/*physiopathology,Middle Aged,Myocardial Infarction/etiology,Prognosis,Prospective Studies,Sex Factors,Smoking/adverse effects,Stress, Psychological/physiopathology
ISSN: 0003-3197
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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