Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/22941
Full metadata record
DC FieldValueLanguage
dc.contributor.authorXanthopoulou, M. N.en
dc.contributor.authorHadjikakou, S. K.en
dc.contributor.authorHadjiliadis, N.en
dc.contributor.authorSchurmann, M.en
dc.contributor.authorJurkschat, K.en
dc.contributor.authorBinolis, J.en
dc.contributor.authorKarkabounas, S.en
dc.contributor.authorCharalabopoulos, K.en
dc.date.accessioned2015-11-24T19:29:01Z-
dc.date.available2015-11-24T19:29:01Z-
dc.identifier.issn1565-3633-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22941-
dc.rightsDefault Licence-
dc.titleCommunication: synthesis of a novel triphenyltin(IV) derivative of 2- mercaptonicotinic acid with potent cytotoxicity in vitroen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1155/S1565363303000189-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18365056-
heal.identifier.secondaryhttp://downloads.hindawi.com/journals/bca/2003/346578.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2003-
heal.abstractA novel triphenyltin(IV) derivative of 2-mercaptonicotinic acid (H(2)mna) of formula {[(C(6)H(5))(3)Sn](2)(mna).[(CH(3))(2)CO]} (1) has been synthesized and characterized by elemental analysis and (1)H, (13)C-NMR, and FT-IR spectroscopic techniques. The crystal structure of complex (1) has been determined by single crystal X-ray diffraction analysis at 173(1) K. Compound (1) contains two triphenyltin moieties linked by a doubly de-protonated 2,mercaptonicotinic acid (H(>2)mna). It is an example of a pentacoordinated Ph(3)SnXY system with an axial-equatorial arrangement of the phenyl groups at Sn(1). Compound (1), exhibits potent, in vitro, cytotoxicity against sarcoma cancer cells (mesenchymal tissue) from the Wistar rat, polycyclic aromatic hydrocarbons (PAH, benzo[a]pyrene) carcinogenesis.en
heal.journalNameBioinorg Chem Applen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

Files in This Item:
File Description SizeFormat 
Xanthopoulou-2003-Communication_ synth.pdf476.93 kBAdobe PDFView/Open


This item is licensed under a Creative Commons License Creative Commons