Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/22302
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dc.contributor.authorKatsanos, K. H.en
dc.contributor.authorVermeire, S.en
dc.contributor.authorChristodoulou, D. K.en
dc.contributor.authorRiis, L.en
dc.contributor.authorWolters, F.en
dc.contributor.authorOdes, S.en
dc.contributor.authorFreitas, J.en
dc.contributor.authorHoie, O.en
dc.contributor.authorBeltrami, M.en
dc.contributor.authorFornaciari, G.en
dc.contributor.authorClofent, J.en
dc.contributor.authorBodini, P.en
dc.contributor.authorVatn, M.en
dc.contributor.authorNunes, P. B.en
dc.contributor.authorMoum, B.en
dc.contributor.authorMunkholm, P.en
dc.contributor.authorLimonard, C.en
dc.contributor.authorStockbrugger, R.en
dc.contributor.authorRutgeerts, P.en
dc.contributor.authorTsianos, E. V.en
dc.date.accessioned2015-11-24T19:23:25Z-
dc.date.available2015-11-24T19:23:25Z-
dc.identifier.issn1421-9867-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22302-
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAgeden
dc.subjectBiopsyen
dc.subjectChi-Square Distributionen
dc.subjectEurope/epidemiologyen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subjectHumansen
dc.subjectInflammatory Bowel Diseases/complications/*epidemiology/pathologyen
dc.subjectIntestinal Neoplasms/complications/*epidemiology/pathologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPrevalenceen
dc.subjectProspective Studiesen
dc.subjectQuestionnairesen
dc.subjectRisken
dc.titleDysplasia and cancer in inflammatory bowel disease 10 years after diagnosis: results of a population-based European collaborative follow-up studyen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1159/000104731-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/17598963-
heal.identifier.secondaryhttp://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=000104731&Ausgabe=233103&ProduktNr=223838&filename=000104731.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2007-
heal.abstractOBJECTIVE: To determine dysplasia and cancer in the 1991-2004 European Collaborative Inflammatory Bowel Disease (EC-IBD) Study Group cohort. PATIENTS AND METHODS: A patient questionnaire and a physician per patient form were completed for each of the 1,141 inflammatory bowel disease patients (776 ulcerative colitis/365 Crohn's disease) from 9 centers (7 countries) derived from the EC-IBD cohort. Rates of detection of intestinal cancer and dysplasia as well as extra-intestinal neoplasms were computed. RESULTS: Patient follow-up time was 10.3 +/- 0.8 (range 9.4-11) years. The mean age of the whole group of IBD patients was 37.8 +/- 11.3 (range 16-76) years. Thirty-eight patients (3.3%; 26 with ulcerative colitis/12 with Crohn's disease, 21 males/17 females, aged 61.3 +/- 13.4, range 33-77 years), were diagnosed with 42 cancers. Cancers occurred 5.4 +/- 3.3 (range 0-11) years after inflammatory bowel disease diagnosis. Colorectal cancer was diagnosed in 8 (1 Crohn's disease and 7 ulcerative colitis patients--0.3 and 0.9% of the Crohn's disease and ulcerative colitis cohort, respectively) of 38 patients and 30 cancers were extra-intestinal. Four of 38 patients (10.5%) were diagnosed as having 2 cancers and they were younger compared to patients with one cancer (p = 0.0008). There was a trend for a higher prevalence of intestinal cancer in the northern centers (0.9%) compared to southern centers (0.3%, p = NS). Southern centers had more cases of extra-intestinal cancer compared to northern centers (2 vs. 3.8%, p = 0.08). Ten patients (0.9%; 8 with ulcerative colitis/2 with Crohn's disease, 8 males, aged 62.3 +/- 14.1 years) had colorectal dysplasia. CONCLUSIONS: In the first decade of the EC-IBD Study Group cohort follow-up study, the prevalence of cancer was as expected with most patients having a single neoplasm and an extra-intestinal neoplasm. In northern centers there was a trend for more intestinal cancers, while in southern centers there was a trend for more extra-intestinal cancers compared to northern centers.en
heal.journalNameDigestionen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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