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DC Field | Value | Language |
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dc.contributor.author | Katsanos, K. H. | en |
dc.contributor.author | Vermeire, S. | en |
dc.contributor.author | Christodoulou, D. K. | en |
dc.contributor.author | Riis, L. | en |
dc.contributor.author | Wolters, F. | en |
dc.contributor.author | Odes, S. | en |
dc.contributor.author | Freitas, J. | en |
dc.contributor.author | Hoie, O. | en |
dc.contributor.author | Beltrami, M. | en |
dc.contributor.author | Fornaciari, G. | en |
dc.contributor.author | Clofent, J. | en |
dc.contributor.author | Bodini, P. | en |
dc.contributor.author | Vatn, M. | en |
dc.contributor.author | Nunes, P. B. | en |
dc.contributor.author | Moum, B. | en |
dc.contributor.author | Munkholm, P. | en |
dc.contributor.author | Limonard, C. | en |
dc.contributor.author | Stockbrugger, R. | en |
dc.contributor.author | Rutgeerts, P. | en |
dc.contributor.author | Tsianos, E. V. | en |
dc.date.accessioned | 2015-11-24T19:23:25Z | - |
dc.date.available | 2015-11-24T19:23:25Z | - |
dc.identifier.issn | 1421-9867 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/22302 | - |
dc.rights | Default Licence | - |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Biopsy | en |
dc.subject | Chi-Square Distribution | en |
dc.subject | Europe/epidemiology | en |
dc.subject | Female | en |
dc.subject | Follow-Up Studies | en |
dc.subject | Humans | en |
dc.subject | Inflammatory Bowel Diseases/complications/*epidemiology/pathology | en |
dc.subject | Intestinal Neoplasms/complications/*epidemiology/pathology | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Prevalence | en |
dc.subject | Prospective Studies | en |
dc.subject | Questionnaires | en |
dc.subject | Risk | en |
dc.title | Dysplasia and cancer in inflammatory bowel disease 10 years after diagnosis: results of a population-based European collaborative follow-up study | en |
heal.type | journalArticle | - |
heal.type.en | Journal article | en |
heal.type.el | Άρθρο Περιοδικού | el |
heal.identifier.primary | 10.1159/000104731 | - |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/17598963 | - |
heal.identifier.secondary | http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=000104731&Ausgabe=233103&ProduktNr=223838&filename=000104731.pdf | - |
heal.language | en | - |
heal.access | campus | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.publicationDate | 2007 | - |
heal.abstract | OBJECTIVE: To determine dysplasia and cancer in the 1991-2004 European Collaborative Inflammatory Bowel Disease (EC-IBD) Study Group cohort. PATIENTS AND METHODS: A patient questionnaire and a physician per patient form were completed for each of the 1,141 inflammatory bowel disease patients (776 ulcerative colitis/365 Crohn's disease) from 9 centers (7 countries) derived from the EC-IBD cohort. Rates of detection of intestinal cancer and dysplasia as well as extra-intestinal neoplasms were computed. RESULTS: Patient follow-up time was 10.3 +/- 0.8 (range 9.4-11) years. The mean age of the whole group of IBD patients was 37.8 +/- 11.3 (range 16-76) years. Thirty-eight patients (3.3%; 26 with ulcerative colitis/12 with Crohn's disease, 21 males/17 females, aged 61.3 +/- 13.4, range 33-77 years), were diagnosed with 42 cancers. Cancers occurred 5.4 +/- 3.3 (range 0-11) years after inflammatory bowel disease diagnosis. Colorectal cancer was diagnosed in 8 (1 Crohn's disease and 7 ulcerative colitis patients--0.3 and 0.9% of the Crohn's disease and ulcerative colitis cohort, respectively) of 38 patients and 30 cancers were extra-intestinal. Four of 38 patients (10.5%) were diagnosed as having 2 cancers and they were younger compared to patients with one cancer (p = 0.0008). There was a trend for a higher prevalence of intestinal cancer in the northern centers (0.9%) compared to southern centers (0.3%, p = NS). Southern centers had more cases of extra-intestinal cancer compared to northern centers (2 vs. 3.8%, p = 0.08). Ten patients (0.9%; 8 with ulcerative colitis/2 with Crohn's disease, 8 males, aged 62.3 +/- 14.1 years) had colorectal dysplasia. CONCLUSIONS: In the first decade of the EC-IBD Study Group cohort follow-up study, the prevalence of cancer was as expected with most patients having a single neoplasm and an extra-intestinal neoplasm. In northern centers there was a trend for more intestinal cancers, while in southern centers there was a trend for more extra-intestinal cancers compared to northern centers. | en |
heal.journalName | Digestion | en |
heal.journalType | peer-reviewed | - |
heal.fullTextAvailability | TRUE | - |
Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ |
Files in This Item:
File | Description | Size | Format | |
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Katsanos-2007-Dysplasia and cancer.pdf | 214.62 kB | Adobe PDF | View/Open Request a copy |
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