Effect of acute ventricular pressure changes on QRS duration (Journal article)

Sideris, D. A./ Toumanidis, S. T./ Kostopoulos, K./ Pittaras, A./ Spyropoulos, G. S./ Kostis, E. B./ Moulopoulos, S. D.


The effect of acute changes in ventricular pressure is examined on the QRS duration to clarify the mechanism of ventricular pressure-related arrhythmogenesis. Ventricular pressure was changed acutely by arterial transfusion-bleeding into an open-air ventricular pressure reservoir that was either off or on a metaraminol intravenous drip. While maintaining ventricular pressure at several levels, the QRS duration was measured at 200 mm/s paper speed. The QRS duration correlated significantly with the left ventricular pressure in all 14 dogs examined. An average change in ventricular by 100 mmHg was associated with a change of about 18% in the QRS duration. An acute ventricular pressure elevation impairs the ventricular conduction, which may contribute to ventricular pressure-related arrhythmogenicity.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Animals,Aorta/physiopathology,Arrhythmias, Cardiac/*etiology/physiopathology,Blood Pressure/drug effects/physiology,Blood Volume,Dogs,*Electrocardiography/drug effects,Heart Conduction System/drug effects/physiopathology,Infusions, Intravenous,Metaraminol/administration & dosage/pharmacology,Regression Analysis,Tachycardia, Ventricular/etiology/physiopathology,Time Factors,Ventricular Pressure/drug effects/*physiology
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/22250
ISSN: 0022-0736
Link: http://www.ncbi.nlm.nih.gov/pubmed/7930981
http://ac.els-cdn.com/S0022073694800022/1-s2.0-S0022073694800022-main.pdf?_tid=e458c436a7952f94647ecc821edf45a0&acdnat=1337847578_d7e78753cd8a99ea3ac3a3be0ea532fe
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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