Effect of intraperitoneal saline irrigation at different temperatures on adhesion formation (Journal article)

Kappas, A. M./ Fatouros, M./ Papadimitriou, K./ Katsouyannopoulos, V./ Cassioumis, D.


This study was designed to examine the influence of saline irrigation at different temperatures on adhesion/formation in the rat. Saline irrigation through a laparotomy incision was performed at the following temperatures: 30 degrees C, 34 degrees C, 37 degrees C, 40 degrees C, 45 degrees C, 50 degrees C, 55 degrees C, and 60 degrees C. The control group (Gc, n = 20) underwent laparotomy without irrigation. Adhesions were found in: 5/20 animals of the Gc (all slight); 6/20 of the 30 degrees C group (all slight); 6/20 of the 34 degrees C group (all slight); 6/20 of the 37 degrees C group (all slight); 12/20 of the 40 degrees C group (all slight); 12/20 of the 45 degrees C group (11 slight, 1 moderate); 14/20 of the 50 degrees C group (12 slight, 2 moderate); 18/19 of the 55 degrees C group (2 slight, 6 moderate, 10 marked); and 18/18 of the 60 degrees C group (1 moderate, 8 marked, 9 massive). These results indicate that saline irrigation below body temperature does not prevent adhesions whereas warmed saline encourages adhesion formation in the rat.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Animals,*Intraoperative Care,Peritoneal Diseases/*etiology,Peritoneal Lavage/*adverse effects,Rats,Rats, Inbred Strains,*Sodium Chloride,*Temperature,Tissue Adhesions/etiology
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/22201
ISSN: 0007-1323
Link: http://www.ncbi.nlm.nih.gov/pubmed/3179657
http://onlinelibrary.wiley.com/store/10.1002/bjs.1800750908/asset/1800750908_ftp.pdf?v=1&t=h1xdquu1&s=6ee55da46e26ed37afb5c8a8561a76a424263b33
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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