Erectile function and male reproduction in men with spinal cord injury: a review (Journal article)

Dimitriadis, F./ Karakitsios, K./ Tsounapi, P./ Tsambalas, S./ Loutradis, D./ Kanakas, N./ Watanabe, N. T./ Saito, M./ Miyagawa, I./ Sofikitis, N.


Spinal cord injury (SCI) in men results in defects in erectile function, ejaculatory process and male reproductive potential. There are alterations in the capacity of men with SCI to achieve reflexogenic, psychogenic and nocturnal erections. The sexual function in different stages after SCI and the types of erections depend mainly on the completeness of the injury and the level of neurological damage. Furthermore, most of the SCI men demonstrate defects concerning the entrance of semen into the posterior urethra and the expulsion of the semen through the penile urethra and the urethral orifice. In addition, SCI men develop defects in the secretory function of the Leydig cells, Sertoli cells and the male accessory genital glands. The overall result is a decreased quality of the semen is recovered either with penile vibratory stimulation (PVS) or with electroejaculation. Nowadays the therapeutic andrological approach of SCI men focuses on achievement of erectile function, recovery of spermatozoa and assisted reproductive technology. The first line of therapy recommended for infertility in SCI men is collection of semen via PVS with concomitant evaluation of total motile sperm yields for assisted conception which may include intravaginal insemination, intrauterine insemination, or in vitro fertilisation/intracytoplasmic sperm injection. Patients failing PVS may be referred for electroejaculation or surgical sperm retrieval.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Autonomic Nervous System/physiopathology,Erectile Dysfunction/*etiology,Humans,Infertility, Male/*etiology/therapy,Male,*Reproductive Techniques, Assisted,Spinal Cord Injuries/*complications/physiopathology
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/21884
ISSN: 1439-0272
Link: http://www.ncbi.nlm.nih.gov/pubmed/20500744
http://onlinelibrary.wiley.com/store/10.1111/j.1439-0272.2009.00969.x/asset/j.1439-0272.2009.00969.x.pdf?v=1&t=h0p89o5o&s=dc1b49d46c4617f01da0e47e6d04d531aacd7718
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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