Erythema nodosum: the underlying conditions (Journal article)

Psychos, D. N./ Voulgari, P. V./ Skopouli, F. N./ Drosos, A. A./ Moutsopoulos, H. M.

Erythema nodosum (EN) is a cutaneous reaction consisting of inflammatory, tender nodular lesions and is associated with a wide variety of disease processes. The aim of our study was to investigate the frequency of different aetiologies of EN. One hundred and thirty-two EN patients were investigated in a prospective study during the period 1984-1990. The evaluation of all patients began with a medical and family history and completed with a thorough physical examination and detailed laboratory and immunological work-up. In addition, various diagnostic procedures were performed where and when indicated. One hundred and ten patients (83%) were women. Their mean age was 41.0+/-14.0 years, range 18-79 years. In 35% the cause of EN was not found. Sarcoidosis was revealed in 28% of the patients, infections in 17.3% and tuberculosis in 1.5%. Other aetiologic factors were Adamantiadis-Behcet's syndrome (3.8%), pregnancy (6%), oral contraceptives (3.8%) and other drugs (3.8%). The aetiology of EN was not found in 35% of the patients. Sarcoidosis and infections were frequent causes of EN, whereas autoimmune rheumatic diseases rarely cause EN.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Adolescent,Adult,Aged,Erythema Nodosum/*etiology/pathology/physiopathology,Female,Greece,Humans,Incidence,Infection/complications/epidemiology,Male,Middle Aged,Prospective Studies,Sarcoidosis/complications/epidemiology,Tuberculosis/complications/epidemiology
ISSN: 0770-3198
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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