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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Ioannidis, J. P. | en |
| dc.contributor.author | Katsifis, G. E. | en |
| dc.contributor.author | Stavropoulos, E. D. | en |
| dc.contributor.author | Manoussakis, M. N. | en |
| dc.contributor.author | Moutsopoulos, H. M. | en |
| dc.date.accessioned | 2015-11-24T19:17:39Z | - |
| dc.date.available | 2015-11-24T19:17:39Z | - |
| dc.identifier.issn | 1462-0324 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21800 | - |
| dc.rights | Default Licence | - |
| dc.subject | Aged | en |
| dc.subject | Aged, 80 and over | en |
| dc.subject | Aging/*immunology | en |
| dc.subject | Antibodies, Anticardiolipin/blood | en |
| dc.subject | Antibodies, Antinuclear/blood | en |
| dc.subject | Autoantibodies/*blood | en |
| dc.subject | Cohort Studies | en |
| dc.subject | DNA, Single-Stranded/immunology | en |
| dc.subject | Female | en |
| dc.subject | Follow-Up Studies | en |
| dc.subject | Humans | en |
| dc.subject | Male | en |
| dc.subject | Proportional Hazards Models | en |
| dc.subject | Rheumatoid Factor/blood | en |
| dc.subject | Risk Factors | en |
| dc.subject | Survival Analysis | en |
| dc.subject | Survival Rate | en |
| dc.title | Evaluation of the association of autoantibodies with mortality in the very elderly: a cohort study | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/12595636 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2003 | - |
| heal.abstract | OBJECTIVE: To evaluate whether autoantibodies in the absence of rheumatic diseases increase the risk of mortality among very elderly subjects who are otherwise in good functional condition. METHODS: Autoantibodies were measured in 1987 in 156 elderly nursing home residents (median age 84 yr) who were followed subsequently over 14.6 yr. RESULTS: Eleven subjects had anticardiolipin antibodies, 30 had rheumatoid factor and 19 had antibodies to single-stranded DNA (ssDNA). Other autoantibodies were more rare. During follow-up, 144 subjects died. Adjusting for age as a time-dependent covariate, the hazard ratio for death was 0.71 [95% confidence interval (CI) 0.38-1.32] for anticardiolipin antibodies, 0.93 (95% CI 0.60-1.41) for rheumatoid factor, 1.08 (95% CI 0.65-1.79) for antibodies to ssDNA, and 0.99 (95% CI, 0.70-1.41) for any autoantibody. Hazard ratios were similar when adjusted also for sex and clinical conditions. CONCLUSION: Our results exclude the possibility that the autoantibodies evaluated increase substantially the risk of death among very elderly subjects in good functional condition. | en |
| heal.journalName | Rheumatology (Oxford) | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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