Expression of adhesion molecules during normal pregnancy (Journal article)

Pafilis, J./ Batistatou, A./ Iliopoulou, A./ Tsanou, E./ Bakogiannis, A./ Dassopoulos, G./ Charalabopoulos, K.

We review the available information regarding the role of adhesive molecules as potential participants in the complex events of fertilization, embryogenesis, implantation and placentation. Studies that specifically relate to the expression and modulation of adhesive molecules in fertilization, embryogenesis, and implantation have been identified in the literature and by Medline searches. Cell-cell and cell-extracellular matrix interactions play a critical role in various developmental processes and in the cascade of events that lead to implantation and to the normal development of the fetus during pregnancy. Adhesion molecules influence, directly or indirectly, numerous aspects of cell behaviour, cell migration, cell growth, cell survival, cell proliferation, angiogenesis, invasion and metastasis.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Animals,Cell Adhesion Molecules/*biosynthesis,Cell Movement/physiology,Cell Proliferation,Cell Survival/physiology,Embryo Implantation/physiology,Female,Fetal Development/physiology,Gene Expression Regulation/*physiology,Humans,Neovascularization, Physiologic/physiology,Placentation/physiology,Pregnancy/*metabolism
ISSN: 0302-766X
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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