Hearing loss in progressive systemic sclerosis patients: a comparative study (Journal article)

Kastanioudakis, I./ Ziavra, N./ Politi, E. N./ Exarchakos, G./ Drosos, A. A./ Skevas, A.


OBJECTIVE: To investigate the middle and inner ear involvement in patients with progressive systemic sclerosis (PSS). STUDY DESIGN AND SETTINGS: We prospectively evaluated 34 PSS patients. All patients underwent a complete ear-nose-throat physical examination and audiological evaluation with pure tone, impedance, and speech audiometry. In addition, systemic manifestations of the disease and drug therapy were recorded. Finally, all patients were tested for the presence of autoantibodies. The results were compared with those of 45 age-matched healthy subjects. RESULTS: We found a sensorineural hearing loss in 20% and mixed type hearing loss in 3.3% of the patients. There was no correlation of hearing loss with age, systemic manifestations of the disease, presence of autoantibodies, and drug therapy. Ten percent of the patients had patulous eustachian tubes. CONCLUSION: One fourth of PSS patients had a hearing loss affecting the middle and mainly the high frequencies. This is a lower percentage than that reported by other investigators. A significant prevalence of bilateral patulous eustachian tubes was noticed as well. Further investigation is needed for a better understanding of the mechanism of ear damage in PSS patients.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Adult,Aged,Audiometry, Pure-Tone,Disease Progression,Female,Hearing Loss, Sensorineural/*etiology,Humans,Male,Middle Aged,Prospective Studies,Scleroderma, Systemic/*complications
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/21290
ISSN: 0194-5998
Link: http://www.ncbi.nlm.nih.gov/pubmed/11337656
http://oto.sagepub.com/content/124/5/522
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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