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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Konitsiotis, S. | en |
| dc.contributor.author | Kafetzopoulos, E. | en |
| dc.date.accessioned | 2015-11-24T19:14:16Z | - |
| dc.date.available | 2015-11-24T19:14:16Z | - |
| dc.identifier.issn | 0014-2999 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21277 | - |
| dc.rights | Default Licence | - |
| dc.subject | Analysis of Variance | en |
| dc.subject | Animals | en |
| dc.subject | Apomorphine/pharmacology | en |
| dc.subject | Behavior, Animal/*drug effects | en |
| dc.subject | Benzazepines/*pharmacology | en |
| dc.subject | Corpus Striatum/*drug effects | en |
| dc.subject | Dopamine Antagonists | en |
| dc.subject | Injections, Intraperitoneal | en |
| dc.subject | Injections, Intraventricular | en |
| dc.subject | Male | en |
| dc.subject | Motor Activity/*drug effects | en |
| dc.subject | Rats | en |
| dc.subject | Rats, Inbred Strains | en |
| dc.subject | Receptors, Dopamine/*drug effects | en |
| dc.subject | Receptors, Dopamine D1 | en |
| dc.subject | Receptors, Dopamine D2 | en |
| dc.subject | Sulpiride/*pharmacology | en |
| dc.title | Topography of dopamine D-1 and D-2 receptor-mediated rotation after intrastriatal injections of dopamine-related drugs in normosensitive rats | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/2142084 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 1990 | - |
| heal.abstract | Naive rats were challenged systematically with apomorphine after receiving unilateral dorsal or ventral intracaudate injections of the dopamine D-1 receptor antagonist, SCH23390, or the D-2 receptor antagonist, sulpiride. Sulpiride injections into both the dorsal and ventral striatum induced a robust ipsilateral rotation, while SCH23390 elicited a weaker ipsilateral rotation only on injection into the ventral striatum. Both drugs were ineffective in saline-treated rats, although sulpiride injections into the ventral striatum after systemic saline elicited a small ipsilateral preference. The results from this rotational model mediated by normosensitive receptors indicate that only dopamine D-1 receptors in the ventral striatum mediate rotation while D-2 receptors in both striatal regions mediate rotation. A functional dichotomy between these two neostriatal regions is thus proposed. | en |
| heal.journalName | Eur J Pharmacol | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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