Heterotopic ossification in systemic sclerosis (Journal article)

Botzoris, V./ Argyropoulou, M. I./ Voulgari, P. V./ Zikou, A. K./ Drosos, A. A.


Although myopathy or myositis may occur in systemic sclerosis (SSc) as well as soft tissue calcification, ossification is not a feature of the disease. Here we present an unusual case of extended calcification and, to a lesser degree, ossification of the right gluteal region, lateral thigh, and knee, with associated myopathy and functional impairment. Heterotopic ossification (HO), or myositis ossificans, has not been reported so far in scleroderma patients, making this case, in our opinion, unique and interesting. However, differential diagnosis from other causes of extraskeletal ossification, such as tumours or tumour-like conditions, is required.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Acetaminophen/therapeutic use,Colchicine/therapeutic use,Drug Therapy, Combination,Etidronic Acid/analogs & derivatives/therapeutic use,Humans,Knee Joint/pathology,Male,Middle Aged,Ossification, Heterotopic/*complications/drug therapy/*pathology/radiography,Pain Measurement,Prognosis,Risk Assessment,Scleroderma, Systemic/*complications/drug therapy/*pathology/radiography,Severity of Illness Index,Thigh/pathology,Tomography, X-Ray Computed,Treatment Outcome
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/21243
ISSN: 1502-7732
Link: http://www.ncbi.nlm.nih.gov/pubmed/19337947
http://informahealthcare.com/doi/abs/10.1080/03009740902776919
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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