Histologic comparison of vibrating guidewire with conventional guidewire technique in an experimental coronary in vivo model (Journal article)

Katsouras, C. S./ Michalis, L. K./ Malamou-Mitsi, V. D./ Niokou, D./ Giogiakas, V./ Nikas, D./ Massouras, G./ Dallas, P./ Tsetis, D. K./ Sideris, D. A./ Rees, M. R.

PURPOSE: To compare the damage caused by vibrating guidewire manipulation and conventional guidewire manipulation of soft coronary wires in normal sheep coronary arteries. METHODS: Using an intact sheep model the two methods of passing a coronary guidewire down a normal coronary artery under fluoroscopic screening control were studied. The resulting arterial damage caused by the two techniques was studied histologically. The severity of damage was scored from 1 (no damage) to 4 (severe damage) and expressed as: (a) percentage of damaged sections, (b) mean damage score per section and (c) percentage of sections suffering the most severe degree of damage (scores 3 and 4). RESULTS: One hundred and sixty-eight sections were studied. The percentage of damaged sections was lower in the vibrating guidewire group (p = 0.004). The mean damage score and the percentage of sections with a damage score of 3 or 4 were smaller in the vibrating guidewire group than in the conventional guidewire manipulation group (p = 0.001 and p = 0.009, respectively). CONCLUSIONS: Both methods of guidewire manipulation cause identifiable vascular damage. The extent and severity of damage appear greater when the guidewire is manipulated manually.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Angioplasty, Balloon/*adverse effects/*instrumentation/methods,Animals,Coronary Vessels/*injuries/*pathology,Equipment Design/adverse effects,Male,Models, Animal,Sheep,Vibration
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/21199
ISSN: 0174-1551
Link: http://www.ncbi.nlm.nih.gov/pubmed/14753304
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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