Immediate post-operative effects of tracheotomy on respiratory function during mechanical ventilation (Journal article)

Amygdalou, A./ Dimopoulos, G./ Moukas, M./ Katsanos, C./ Katagi, A./ Mandragos, C./ Constantopoulos, S. H./ Behrakis, P. K./ Vassiliou, M. P.


INTRODUCTION: Tracheotomy is widely performed in the intensive care unit after long-term oral intubation. The present study investigates the immediate influence of tracheotomy on respiratory mechanics and blood gases during mechanical ventilation. METHODS: Tracheotomy was performed in 32 orally intubated patients for 10.5 +/- 4.66 days (all results are means +/- standard deviations). Airway pressure, flow and arterial blood gases were recorded immediately before tracheotomy and half an hour afterwards. Respiratory system elastance (Ers), resistance (Rrs) and end-expiratory pressure (EEP) were evaluated by multiple linear regression. Respiratory system reactance (Xrs), impedance (Zrs) and phase angle (phirs) were calculated from Ers and Rrs. Comparisons of the mechanical parameters, blood gases and pH were performed with the aid of the Wilcoxon signed-rank test (P = 0.05). RESULTS: Ers increased (7 +/- 11.3%, P = 0.001), whereas Rrs (-16 +/- 18.4%, P = 0.0003), Xrs (-6 +/- 11.6%, P = 0.006) and phi rs (-14.3 +/- 16.8%, P = <0.001) decreased immediately after tracheotomy. EEP, Zrs, blood gases and pH did not change significantly. CONCLUSION: Lower Rrs but also higher Ers were noted immediately after tracheotomy. The net effect is a non-significant change in the overall Rrs (impedance) and the effectiveness of respiratory function. The extra dose of anaesthetics (beyond that used for sedation at the beginning of the procedure) or a higher FiO2 (fraction of inspired oxygen) during tracheotomy or aspiration could be related to the immediate elastance increase.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Adult,Aged,Airway Resistance/physiology,Blood Gas Analysis,Female,Humans,Intensive Care Units,Male,Middle Aged,Monitoring, Physiologic,Postoperative Period,Regression Analysis,*Respiration, Artificial,*Respiratory Mechanics,Tidal Volume/physiology,*Tracheotomy,Treatment Outcome,Work of Breathing/physiology
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/21015
ISSN: 1466-609X
Link: http://www.ncbi.nlm.nih.gov/pubmed/15312224
http://ccforum.com/content/pdf/cc2886.pdf
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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