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  4. Τμήμα Ιατρικής
  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/20400
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dc.contributor.authorElisaf, M. S.en
dc.contributor.authorSiamopoulos, K. C.en
dc.contributor.authorTselegarides, T. J.en
dc.contributor.authorBairaktari, E. T.en
dc.contributor.authorGoudevenos, J. A.en
dc.contributor.authorTselepis, A. D.en
dc.contributor.authorTsolas, O. E.en
dc.contributor.authorSideris, D. A.en
dc.date.accessioned2015-11-24T19:07:05Z-
dc.date.available2015-11-24T19:07:05Z-
dc.identifier.issn0167-5273-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20400-
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectApolipoprotein A-I/blood/geneticsen
dc.subjectApolipoproteins B/blood/geneticsen
dc.subjectCase-Control Studiesen
dc.subjectCholesterol/blooden
dc.subjectCholesterol, HDL/blooden
dc.subjectCholesterol, LDL/blooden
dc.subjectCoronary Angiographyen
dc.subjectCoronary Disease/blood/*complications/geneticsen
dc.subjectFemaleen
dc.subjectGreeceen
dc.subjectHumansen
dc.subjectHypercholesterolemia/blood/complicationsen
dc.subjectHyperlipidemias/blood/*complications/geneticsen
dc.subjectHyperlipoproteinemias/blood/complicationsen
dc.subjectHypertriglyceridemia/blood/complicationsen
dc.subjectHypolipoproteinemias/blood/complicationsen
dc.subjectLipoprotein(a)/blooden
dc.subjectLipoproteins, HDL/blood/geneticsen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPhenotypeen
dc.subjectRisk Factorsen
dc.subjectTriglycerides/blooden
dc.titleLipid abnormalities in Greek patients with coronary artery diseaseen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/9158172-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0167527396029166/1-s2.0-S0167527396029166-main.pdf?_tid=96c136354eb4ca5d01bb0b44a4c448e7&acdnat=1333530900_8d6eaf1420c3922463919ae53e3b4436-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1997-
heal.abstractLipid abnormalities are major risk factors for premature coronary artery disease (CAD). However, the type and prevalence of dyslipidemia in these patients have not been well characterised, especially in some ethnic groups. The purpose of the present work was to determine the lipid disorders in patients of Northwestern Greece with premature CAD. The study population comprised of 132 men and 38 women who underwent elective diagnostic arteriography in our University Hospital. Subjects with > or = 1 lesion that narrowed the lumen of any of the 15 coronary artery segments by > or = 70% were considered to be CAD cases (n=108), whereas those with narrowing < 70% were excluded (n=54). Asymptomatic subjects (n=104) matched for age and sex were taken as controls. Compared with the controls, patients with premature CAD had increased serum levels of total cholesterol, LDL cholesterol, triglycerides, Apo B, and Lp(a), and decreased serum levels of HDL cholesterol and Apo A1. A lipoprotein or apolipoprotein abnormality was identified in 89 CAD patients (82.4%). The increased serum Apo B level (> 130 mg/dl) was the most common lipid abnormality observed in 72 patients. However, the most prevalent dyslipidemic phenotypes in our patients were type IIA followed by hypoalpha and hyperApoB. Compared to the control population, CAD patients had increased incidence of IIA and hypoalpha phenotypes. On the contrary, a normal lipoprotein phenotype was more common in the control population compared to CAD patients (56.7% vs. 17.6%, P<0.001). We conclude that the majority of Greek patients with premature CAD exhibit lipid and lipoprotein abnormalities, which to a large extent can be defined by determining the traditional lipid parameters (total cholesterol, LDL cholesterol, HDL cholesterol and triglycerides). However, in some cases the value of the quantification of other lipid parameters such as apolipoproteins and Lp(a) should be taken into account.en
heal.journalNameInt J Cardiolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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