Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/20217
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dc.contributor.authorParaskevaidis, E.en
dc.contributor.authorKoliopoulos, G.en
dc.contributor.authorKalantaridou, S.en
dc.contributor.authorPappa, L.en
dc.contributor.authorNavrozoglou, I.en
dc.contributor.authorZikopoulos, K.en
dc.contributor.authorLolis, D. E.en
dc.date.accessioned2015-11-24T19:05:37Z-
dc.date.available2015-11-24T19:05:37Z-
dc.identifier.issn0301-2115-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20217-
dc.rightsDefault Licence-
dc.subjectCervical Intraepithelial Neoplasia/etiology/pathology/*therapyen
dc.subjectColposcopyen
dc.subjectDelivery, Obstetric/methodsen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectPapillomavirus Infections/diagnosisen
dc.subjectPerinatal Care/*methodsen
dc.subjectPostpartum Perioden
dc.subjectPregnancyen
dc.subjectPregnancy Complications, Neoplastic/etiology/pathology/*therapy/virologyen
dc.subjectTumor Virus Infections/diagnosisen
dc.subjectUterine Cervical Neoplasms/etiology/*therapy/virologyen
dc.titleManagement and evolution of cervical intraepithelial neoplasia during pregnancy and postpartumen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/12128266-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2002-
heal.abstractOBJECTIVE: To investigate the evolution of cervical intraepithelial neoplasia (CIN), and to evaluate the safety of cytological and colposcopical surveillance of women with CIN during pregnancy. STUDY DESIGN: Ninety-eight women with antenatal cytological and/or colposcopical impression of CIN were followed up during pregnancy with cytology and colposcopy every 2 months. A cytological and colposcopical reevaluation 2 months postpartum was done, and large loop excision of the transformation zone (LLETZ) was performed if appropriate. Punch or loop biopsies were only taken if there was suspicion of microinvasion. RESULTS: In 14 of 39 (35.9%) and in 25 of 52 (48.1%) women with antenatal impression of CIN I and CIN II-III, respectively, there was postnatal impression of regression. Seven women with findings suspicious of microinvasion underwent small loop biopsies during pregnancy, but early stromal invasion (< 1 mm) was seen in just one case. There was one more case of microinvasion (1.5 mm) diagnosed postnatally in which the antenatal impression was of CIN III. 84.6% of the women with regression compared to 67.3% of the women with stable disease or progression had a vaginal delivery (P = 0.057). CONCLUSION: There is a considerable regression rate of CIN after pregnancy possibly attributable to the loss of the dysplastic cervical epithelium during cervical ripening and vaginal delivery. Frequent cytological and colposcopical evaluation seems to be safe. Small loop biopsies are recommended in cases of possible microinvasion.en
heal.journalNameEur J Obstet Gynecol Reprod Biolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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