MRI in the characterization and local staging of testicular neoplasms (Journal article)

Tsili, A. C./ Argyropoulou, M. I./ Giannakis, D./ Sofikitis, N./ Tsampoulas, K.

OBJECTIVE: The purpose of this study was to assess the role of MRI in the preoperative characterization and local staging of testicular neoplasms. SUBJECTS AND METHODS: MRI was performed on 33 patients referred because a testicular mass had been detected clinically and sonographically. Both T1- and T2-weighted sequences were performed with a 1.5-T MRI unit. Gadolinium chelate was administered IV in all cases. We recorded the presence of a lesion and whether the histologic diagnosis of testicular malignancy could have been predicted on the basis of MRI features. For testicular neoplasms, local extension of disease was studied. The MRI findings were correlated with the surgical and histopathologic results. RESULTS: Histologic examination revealed 36 intratesticular lesions, 28 (78%) of which were malignant and eight benign. Thirteen malignant testicular tumors (46%) were confined within the testis, 12 (43%) had invaded the testicular tunicae or epididymis, and three (11%) had invaded the spermatic cord. The sensitivity and specificity of MRI in differentiating benign from malignant intratesticular lesions were 100% (95% CI, 87.9-100%) and 87.5% (95% CI, 52.9-97.7%). The rate of correspondence between MRI and histologic diagnosis in the local staging of testicular tumors was 92.8% (26/28). CONCLUSION: MRI is a good diagnostic tool for the evaluation of testicular disease. It is highly accurate in the preoperative characterization and local staging of testicular neoplasms.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Adolescent,Adult,Aged,Contrast Media,Diagnosis, Differential,Gadolinium DTPA/diagnostic use,Humans,Image Interpretation, Computer-Assisted,Magnetic Resonance Imaging/*methods,Male,Middle Aged,Neoplasm Staging,Prospective Studies,Sensitivity and Specificity,Testicular Neoplasms/*pathology/surgery
URI: https://olympias.lib.uoi.gr/jspui/handle/123456789/19902
ISSN: 1546-3141
Link: http://www.ncbi.nlm.nih.gov/pubmed/20173145
http://www.ajronline.org/content/194/3/682.full.pdf
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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