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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19830
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dc.contributor.authorSioka, C.en
dc.contributor.authorExarchopoulos, T.en
dc.contributor.authorTasiou, I.en
dc.contributor.authorTzima, E.en
dc.contributor.authorFotou, N.en
dc.contributor.authorCapizzello, A.en
dc.contributor.authorRagos, V.en
dc.contributor.authorTsekeris, P.en
dc.contributor.authorFotopoulos, A.en
dc.date.accessioned2015-11-24T19:02:44Z-
dc.date.available2015-11-24T19:02:44Z-
dc.identifier.issn1748-717X-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19830-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectBreast Neoplasms/*pathology/*radiotherapy/*surgeryen
dc.subjectCase-Control Studiesen
dc.subjectChemotherapy, Adjuvanten
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMiddle Ageden
dc.subjectOrganophosphorus Compounds/*pharmacologyen
dc.subjectOrganotechnetium Compounds/*pharmacologyen
dc.subjectPostoperative Perioden
dc.subjectRadiopharmaceuticals/*pharmacologyen
dc.subjectRadiotherapy/*methodsen
dc.subjectRisk Factorsen
dc.subjectTomography, Emission-Computed, Single-Photon/*methodsen
dc.subjectTreatment Outcomeen
dc.titleMyocardial perfusion imaging with (99 m)Tc-tetrofosmin SPECT in breast cancer patients that received postoperative radiotherapy: a case-control studyen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1186/1748-717X-6-151-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/22067743-
heal.identifier.secondaryhttp://www.ro-journal.com/content/pdf/1748-717X-6-151.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2011-
heal.abstractPURPOSE: To evaluate the cardiac toxicity of radiotherapy (RT) in breast cancer (BC) patients employing myocardial perfusion imaging (MPI) with Tc-99 m Tetrofosmin-single photon emission computer tomography (T-SPECT). MATERIALS AND METHODS: We studied 46 BC female patients (28 patients with left and 18 patients with right BC) treated with postoperative RT compared to a control group of 85 age-matched females. The median time of RT to SPECT was 40 months (6-263). RESULTS: Abnormalities in the summed stress score (SSS) were found in 54% of left BC patients, 44.4% of right BC patients, and 32.9% of controls. In left BC patients there were significantly more SSS abnormalities compared to controls (4.0 +/- 3.5 vs 2.6 +/- 2.0, p = 0.05) and possible trend of increased abnormalities of right BC patients (3.7 +/- 3.0 vs 2.6 +/- 2.0, p = 0.14). Multiple regression analysis showed more abnormalities in the MPI of left BC patients compared to controls (SSS, p = 0.0001); Marginal toxicity was also noted in right BC patients (SSS, p = 0.045). No additional toxicity was found in patients that received adjuvant cardiotoxic chemotherapy. All T-SPECT abnormalities were clinically silent. CONCLUSION: The study suggests that radiation therapy to BC patients result in MPI abnormalities but without apparent clinical consequences.en
heal.journalNameRadiat Oncolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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