Novel roles of vitamin D in disease: what is new in 2011? (Journal article)

Makariou, S./ Liberopoulos, E. N./ Elisaf, M. S./ Challa, A.

Vitamin D is a steroid molecule, mainly produced in the skin that regulates the expression of a large number of genes. Until recently its main known role was to control bone metabolism and calcium and phosphorus homeostasis. During the last 2 decades it has been realized that vitamin D deficiency, which is really common worldwide, could be a new risk factor for many chronic diseases, such as the metabolic syndrome and its components, the whole spectrum of cardiovascular diseases, several auto-immune conditions, and many types of cancer as well as all-cause mortality. Except for the great number of epidemiological studies that support the above presumptions, vitamin D receptors (VDRs) have been identified in many tissues and cells. The effect of vitamin D supplementation remains controversial and the need for more persuasive study outcomes is intense.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: *Cardiovascular Diseases/epidemiology/etiology/metabolism,Homeostasis,Humans,Morbidity/trends,Risk Factors,Vitamin D/*metabolism,*Vitamin D Deficiency/complications/epidemiology/metabolism
URI: https://olympias.lib.uoi.gr/jspui/handle/123456789/19695
ISSN: 1879-0828
Link: http://www.ncbi.nlm.nih.gov/pubmed/21767752
http://ac.els-cdn.com/S0953620511000914/1-s2.0-S0953620511000914-main.pdf?_tid=ccf54270fc5e1743708642a3f5caa086&acdnat=1332919328_bbc09fd6be3906ade296f6153d5da009
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

Files in This Item:
File Description SizeFormat 
Makariou-2011-Novel roles of vitam.pdf399.63 kBAdobe PDFView/Open    Request a copy


 Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/19695
  This item is a favorite for 0 people.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.