Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/19224
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ioannidis, J. P. | en |
dc.contributor.author | Lau, J. | en |
dc.date.accessioned | 2015-11-24T18:57:56Z | - |
dc.date.available | 2015-11-24T18:57:56Z | - |
dc.identifier.issn | 1070-3241 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19224 | - |
dc.rights | Default Licence | - |
dc.subject | Bias (Epidemiology) | en |
dc.subject | Data Interpretation, Statistical | en |
dc.subject | Decision Making, Organizational | en |
dc.subject | *Evidence-Based Medicine | en |
dc.subject | Humans | en |
dc.subject | *Meta-Analysis as Topic | en |
dc.subject | Prospective Studies | en |
dc.subject | Reproducibility of Results | en |
dc.subject | Research Design/*standards | en |
dc.subject | Retrospective Studies | en |
dc.subject | Treatment Outcome | en |
dc.title | Pooling research results: benefits and limitations of meta-analysis | en |
heal.type | journalArticle | - |
heal.type.en | Journal article | en |
heal.type.el | Άρθρο Περιοδικού | el |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/10481815 | - |
heal.language | en | - |
heal.access | campus | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.publicationDate | 1999 | - |
heal.abstract | BACKGROUND: Meta-analysis, the systematic and quantitative synthesis of evidence, has developed considerably in the 1990s and is emerging as an important methodology in medical decision making. As a research methodology, meta-analysis has benefits and limitations that must be acknowledged in its application. EXAMPLES OF BENEFITS: The benefits of meta-analysis include the ability to improve the power of small or inconclusive studies to answer questions and the ability to identify sources of diversity across various types of studies. Meta-analysis may reveal how heterogeneity among populations affects the effectiveness of medical interventions in different settings and in different patients. It can also help detect biases, such as publication bias and "Tower of Babel" bias, as well as deficiencies in the design, conduct, analysis, and interpretation of research. In this way, it can also stimulate improvements in the quality of the data needed to optimize medical care. EXAMPLES OF LIMITATIONS: Meta-analysis cannot improve the quality or reporting of the original studies. Other limitations come from misapplications of the method, such as when study diversity is ignored or mishandled in the analysis or when the variability of patient populations, the quality of the data, and the potential for underlying biases are not addressed. CONCLUSIONS: Meta-analysis has promoted the sense that obtaining evidence is a global enterprise and that complete information needs to be evaluated and synthesized to obtain the most unbiased results. Analyzing sources of bias and diversity is essential to performing, understanding, and using meta-analyses in medical care. | en |
heal.journalName | Jt Comm J Qual Improv | en |
heal.journalType | peer-reviewed | - |
heal.fullTextAvailability | TRUE | - |
Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ |
Files in This Item:
There are no files associated with this item.
This item is licensed under a Creative Commons License