Prevalence of primary Sjogren's syndrome in an elderly population (Journal article)

Drosos, A. A./ Andonopoulos, A. P./ Costopoulos, J. S./ Papadimitriou, C. S./ Moutsopoulos, H. M.


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dc.contributor.authorDrosos, A. A.en
dc.contributor.authorAndonopoulos, A. P.en
dc.contributor.authorCostopoulos, J. S.en
dc.contributor.authorPapadimitriou, C. S.en
dc.contributor.authorMoutsopoulos, H. M.en
dc.date.accessioned2015-11-24T18:56:49Z-
dc.date.available2015-11-24T18:56:49Z-
dc.identifier.issn0263-7103-
dc.identifier.urihttp://olympias.lib.uoi.gr/jspui/handle/123456789/19096-
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectAutoantigens/analysisen
dc.subjectFemaleen
dc.subjectGreeceen
dc.subjectHumansen
dc.subjectKeratoconjunctivitis/epidemiologyen
dc.subjectMaleen
dc.subjectQuestionnairesen
dc.subject*RNA, Small Cytoplasmicen
dc.subject*Ribonucleoproteinsen
dc.subjectSalivary Glands/pathologyen
dc.subjectSjogren's Syndrome/diagnosis/*epidemiologyen
dc.subjectXerostomia/epidemiologyen
dc.titlePrevalence of primary Sjogren's syndrome in an elderly populationen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/3365531-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1988-
heal.abstractSixty-two elderly apparently healthy volunteers, inmates of a public nursing home, were examined for evidence of primary Sjogren's syndrome (pSS). Evaluation included a specific questionnaire for subjective xerophthalmia and xerostomia, slit-lamp eye examination after rose Bengal staining. Schirmer's I test, stimulated parotid flow measurement, testing of sera for autoantibodies and labial minor salivary gland biopsy. A greater than or equal to 2+ lip biopsy score on Tarpley's scale was a sine qua non for the diagnosis of Sjogren's syndrome. Labial salivary gland (LSG) biopsy revealed fibrosis and/or fatty infiltration in the majority of the individuals, related to ageing. However, four people had a lip biopsy score of greater than or equal to 2+, which, supplemented by other objective criteria, classified three of them as having pSS. Another four had an LSG biopsy score of 1+, and although they fulfilled other objective criteria, they could not be characterized as pSS. All these individuals were completely asymptomatic, and none of them had anti-Ro(SSA) or anti-La(SSB) autoantibodies. The present study suggests that pSS in elderly people in elderly people is subclinical, benign and relatively common.en
heal.journalNameBr J Rheumatolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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