Prevalence of primary Sjogren's syndrome in an elderly population (Journal article)
Drosos, A. A./ Andonopoulos, A. P./ Costopoulos, J. S./ Papadimitriou, C. S./ Moutsopoulos, H. M.
Full metadata record
|dc.contributor.author||Drosos, A. A.||en|
|dc.contributor.author||Andonopoulos, A. P.||en|
|dc.contributor.author||Costopoulos, J. S.||en|
|dc.contributor.author||Papadimitriou, C. S.||en|
|dc.contributor.author||Moutsopoulos, H. M.||en|
|dc.subject||Aged, 80 and over||en|
|dc.subject||*RNA, Small Cytoplasmic||en|
|dc.title||Prevalence of primary Sjogren's syndrome in an elderly population||en|
|heal.recordProvider||Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής||el|
|heal.abstract||Sixty-two elderly apparently healthy volunteers, inmates of a public nursing home, were examined for evidence of primary Sjogren's syndrome (pSS). Evaluation included a specific questionnaire for subjective xerophthalmia and xerostomia, slit-lamp eye examination after rose Bengal staining. Schirmer's I test, stimulated parotid flow measurement, testing of sera for autoantibodies and labial minor salivary gland biopsy. A greater than or equal to 2+ lip biopsy score on Tarpley's scale was a sine qua non for the diagnosis of Sjogren's syndrome. Labial salivary gland (LSG) biopsy revealed fibrosis and/or fatty infiltration in the majority of the individuals, related to ageing. However, four people had a lip biopsy score of greater than or equal to 2+, which, supplemented by other objective criteria, classified three of them as having pSS. Another four had an LSG biopsy score of 1+, and although they fulfilled other objective criteria, they could not be characterized as pSS. All these individuals were completely asymptomatic, and none of them had anti-Ro(SSA) or anti-La(SSB) autoantibodies. The present study suggests that pSS in elderly people in elderly people is subclinical, benign and relatively common.||en|
|heal.journalName||Br J Rheumatol||en|
|Appears in Collections:||Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)|
Files in This Item:
There are no files associated with this item.
Please use this identifier to cite or link to this item:This item is a favorite for 0 people.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.