Prognostic variables in greek patients with stage II breast cancer: a Hellenic Cooperative Oncology Group study (Journal article)

Fountzilas, G./ Vasilaros, S./ Koukouras, D./ Malamos, N./ Pectasides, D./ Adamou, A./ Nenopoulou, E./ Kiriakou, K./ Zouvani, I./ Katsohis, K./ Kappas, A./ Skopa, C./ Semoglou, C./ Fahantidis, E./ Konstantaras, C./ Vasilaki, E./ Economopoulos, T./ Bacoyiannis, H./ Bafaloukos, D./ Razi, E./ Polichronis, A./ Androulakis, G./ Papaioannou, T./ Pavlidis, N./ Kosmidis, P./ et al.,


The independent effects of several patient, tumor and treatment-related prognostic factors on relapse-free survival (RFS) and overall survival (OS) were assessed by Cox multivariate regression analysis in 988 Greek patients with stage II breast cancer. At a median follow-up time of 83 (range 3.3-131+) months and after the evaluation of all patients together, the number of positive axillary nodes (p < 0.0001), tumor size (p = 0.0024) and tumor grade (p = 0.0008) were identified as significant prognostic factors for RFS. Also, the number of positive nodes (p < 0.0001), tumor size (p = 0.0002) and ER status (p = 0.0001) were found to be significant for OS. These short-term prognostic variables are similar to those reported for this group of patients in other European countries and in the USA.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Adult,Aged,Aged, 80 and over,Antineoplastic Combined Chemotherapy Protocols/therapeutic use,Breast Neoplasms/mortality/*pathology/surgery/*therapy,Chemotherapy, Adjuvant,Combined Modality Therapy,Disease-Free Survival,Europe,Female,Greece,Humans,Lymphatic Metastasis,Medical Records,Menopause,Middle Aged,Multivariate Analysis,Neoplasm Staging,Prognosis,Receptors, Estrogen/analysis,Recurrence,Regression Analysis,Retrospective Studies,Survival Rate,Tamoxifen/therapeutic use,United States
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/18996
ISSN: 0250-7005
Link: http://www.ncbi.nlm.nih.gov/pubmed/9494589
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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