Pulmonary involvement in systemic sclerosis. Association with anti-Scl 70 antibody and digital pitting (Journal article)

Manoussakis, M. N./ Constantopoulos, S. H./ Gharavi, A. E./ Moutsopoulos, H. M.


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dc.contributor.authorManoussakis, M. N.en
dc.contributor.authorConstantopoulos, S. H.en
dc.contributor.authorGharavi, A. E.en
dc.contributor.authorMoutsopoulos, H. M.en
dc.date.accessioned2015-11-24T18:55:31Z-
dc.date.available2015-11-24T18:55:31Z-
dc.identifier.issn0012-3692-
dc.identifier.urihttp://olympias.lib.uoi.gr/jspui/handle/123456789/18895-
dc.rightsDefault Licence-
dc.subjectAutoantibodies/*immunologyen
dc.subjectAutoimmune Diseases/*immunologyen
dc.subjectCentromere/immunologyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMaleen
dc.subject*Nuclear Proteinsen
dc.subjectNucleoproteins/*immunologyen
dc.subjectPulmonary Diffusing Capacityen
dc.subjectPulmonary Fibrosis/*etiology/immunologyen
dc.subjectScleroderma, Systemic/*complications/immunologyen
dc.titlePulmonary involvement in systemic sclerosis. Association with anti-Scl 70 antibody and digital pittingen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/3622029-
heal.identifier.secondaryhttp://chestjournal.chestpubs.org/content/92/3/509.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1987-
heal.abstractThe association of clinical and serologic features of 34 patients with systemic sclerosis was examined. Anti-Scl 70 antibody was found to identify patients with abnormal pulmonary function, particularly impaired diffusion (p less than 0.005), as well as patients with digital pitting scars (p less than 0.025). In addition, the presence of digital pitting scars correlated with impaired diffusion (p less than 0.005), suggesting that interstitial pulmonary disease in systemic sclerosis may, like digital pitting, be secondary to vascular pathology. Anticentromere antibody-positive patients were less likely to have abnormalities of pulmonary function (p less than 0.001).en
heal.journalNameChesten
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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