Sialochemistry of patients with autoimmune rheumatic disease with and without histological manifestations of Sjogren's syndrome (Journal article)

Tsianos, E. B./ Tzioufas, A. G./ Mavridis, A. K./ Sarras, A. K./ Papadimitriou, C. S./ Tsolas, O./ Moutsopoulos, H. M.


Fifty-one patients with autoimmune rheumatic diseases underwent biopsy of the labial minor salivary glands. These patients were divided according to histopathology of lip biopsies into three groups (negative lip biopsy, 1+ and 2+). From all the patients stimulated parotid salivary flow was measured. In the saliva sodium, potassium, magnesium, alpha-amylase, and immunoglobulin levels (IgA, IgG, IgM) were measured. It is shown that patients with advanced chronic inflammatory disease of the minor salivary glands have decreased stimulated salivary flow. However, no statistically significant differences were observed in the biochemical markers tested between the histopathological groups examined.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Arthritis, Rheumatoid/*metabolism/pathology,Autoimmune Diseases/*metabolism/pathology,Female,Humans,Immunoglobulin A/analysis,Magnesium/analysis,Male,Potassium/analysis,Saliva/*analysis,Salivary Glands, Minor/pathology,Sjogren's Syndrome/pathology,Sodium/analysis,alpha-Amylases/analysis
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/18286
ISSN: 0003-4967
Item type: journalArticle
Link: http://www.ncbi.nlm.nih.gov/pubmed/3874609
http://ard.bmj.com/content/44/6/412.full.pdf
Item language: en
Item access scheme: campus
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Publication date: 1985
Abstract: Fifty-one patients with autoimmune rheumatic diseases underwent biopsy of the labial minor salivary glands. These patients were divided according to histopathology of lip biopsies into three groups (negative lip biopsy, 1+ and 2+). From all the patients stimulated parotid salivary flow was measured. In the saliva sodium, potassium, magnesium, alpha-amylase, and immunoglobulin levels (IgA, IgG, IgM) were measured. It is shown that patients with advanced chronic inflammatory disease of the minor salivary glands have decreased stimulated salivary flow. However, no statistically significant differences were observed in the biochemical markers tested between the histopathological groups examined.
Journal name: Ann Rheum Dis
Journal type: peer-reviewed
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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