Sjogren's syndrome in patients with the CREST variant of progressive systemic scleroderma (Journal article)

Drosos, A. A./ Pennec, Y. L./ Elisaf, M. S./ Lamour, A./ Acritidis, N. C./ Jouquan, J. R./ Moutsopoulos, H. M./ Youinou, P.


Twenty-three patients with the CREST (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, telangiectasia) variant of progressive systemic sclerosis, were clinically, histopathologically and serologically examined for the presence of Sjogren's syndrome (SS). Fourteen were found to be positive. No significant difference could be demonstrated between them and the remaining 9. Characteristics of patients with CREST were compared with those of 29 randomly chosen patients with primary SS. Parotid gland enlargement was more frequently present (p less than 0.01) in the latter than in the former. Virtually no patients with CREST with SS had antibodies to Ro(SSA)/La(SSB).
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Autoantibodies/analysis,Calcinosis/complications,Esophageal Motility Disorders/complications,Extremities,Humans,Raynaud Disease/complications,Scleroderma, Localized/*complications,Scleroderma, Systemic/complications/immunology,Sjogren's Syndrome/*complications,Skin Diseases/complications,Syndrome,Telangiectasis/complications
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/18246
ISSN: 0315-162X
Link: http://www.ncbi.nlm.nih.gov/pubmed/1787489
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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