Smoking cessation is associated with reduced long-term mortality and the need for repeat interventions after coronary artery bypass grafting (Journal article)

Papathanasiou, A./ Milionis, H./ Toumpoulis, I./ Kalantzi, K./ Katsouras, C./ Pappas, K./ Michalis, L./ Goudevenos, J.


DESIGN: A prospective study. METHODS: We estimated the impact of smoking cessation on long-term mortality and the need for a revascularization procedure in 1027 patients undergoing a first-ever coronary artery bypass-grafting. RESULTS AND DISCUSSION: Of the 640 active smokers, 44.7% continued smoking after CABG ('current smokers'), and 55.3% quit. During a 5310 patient-years follow-up, with never smokers as the reference group, current smokers (but not quitters) experienced a significant increase in total mortality (hazard ratio 2.6, 95% confidence interval 1.0-6.6) mainly owing to increased cardiovascular mortality (hazard ratio 4.8, 95% confidence interval 1.1-21.4), as well as increased need for a repeat revascularization procedure (hazard ratio 1.7, 95% confidence interval 1.0-2.9).
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Aged,*Coronary Artery Bypass,Coronary Artery Disease/etiology/*mortality/*surgery,Female,Follow-Up Studies,Humans,Kaplan-Meier Estimate,Logistic Models,Male,Mammary Arteries/transplantation,Middle Aged,Proportional Hazards Models,Prospective Studies,Reoperation,Risk Assessment,Saphenous Vein/transplantation,Smoking/*adverse effects,*Smoking Cessation/statistics & numerical data,Time Factors,Treatment Outcome
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/18223
ISSN: 1741-8267
Link: http://www.ncbi.nlm.nih.gov/pubmed/17568247
http://cpr.sagepub.com/content/14/3/448
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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