Subcellular binding of 99Tcm-gluconate in infarcted myocardium in dogs (Journal article)

Ahlberg, N. E./ Cronestrand, R./ Galaris, D./ Grandinson, M./ Rydstrom, J.


Binding of 99Tcm-gluconate on the subcellular level in myocardial infarct tissue in the dog was investigated by means of a fractionated centrifugation technique. High isotope activity/g protein was recorded in the mitochondrial fraction indicating the 99Tcm-gluconate binds preferentially to a protein structure localized in the mitochondria.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Animals,Cell Fractionation,Dogs,Gluconates/administration & dosage/*metabolism,Injections, Intravenous,Mitochondria, Heart/analysis/*metabolism,Myocardial Infarction/*metabolism,Myocardium/analysis/*metabolism,*Organotechnetium Compounds,Potassium Cyanide/pharmacology,Protein Binding,Rats,Technetium/administration & dosage/*metabolism
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/18040
ISSN: 0349-652X
Link: http://www.ncbi.nlm.nih.gov/pubmed/6278858
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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