Subclinical manifestations of autoimmune rheumatic diseases in primary Raynaud's phenomenon (Journal article)

Tzioufas, A. G./ Dalavanga, Y. A./ Constantopoulos, S. H./ Tsianos, E. B./ Papadimitriou, C./ Moutsopoulos, H. M.


Twenty-nine patients with primary Raynaud's phenomenon underwent functional (pulmonary functional studies and oesophageal manometry), histologic (minor salivary gland biopsy) and serologic (autoantibodies) evaluation for subclinical manifestations of autoimmune rheumatic disease (ARD). Seven (24%) has strong evidence and eight (27%) possible evidence of ARD. All patients with strong evidence of ARD had Raynaud's phenomenon with a duration of less than five years. This study suggests that such manifestations are frequent in patients wih primary Raynaud's phenomenon and can be detected with non-aggressive methods which should be used early in the course of their disease.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Adult,Aged,Antibodies, Antinuclear/isolation & purification,Autoimmune Diseases/*complications/diagnosis,Esophagus/physiopathology,Female,Humans,Male,Middle Aged,Raynaud Disease/*complications/diagnosis/physiopathology,Respiratory Function Tests,Rheumatic Diseases/*complications/diagnosis,Salivary Glands/pathology
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/18037
ISSN: 0392-856X
Item type: journalArticle
Link: http://www.ncbi.nlm.nih.gov/pubmed/3876901
Item language: en
Item access scheme: campus
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Publication date: 1985
Abstract: Twenty-nine patients with primary Raynaud's phenomenon underwent functional (pulmonary functional studies and oesophageal manometry), histologic (minor salivary gland biopsy) and serologic (autoantibodies) evaluation for subclinical manifestations of autoimmune rheumatic disease (ARD). Seven (24%) has strong evidence and eight (27%) possible evidence of ARD. All patients with strong evidence of ARD had Raynaud's phenomenon with a duration of less than five years. This study suggests that such manifestations are frequent in patients wih primary Raynaud's phenomenon and can be detected with non-aggressive methods which should be used early in the course of their disease.
Journal name: Clin Exp Rheumatol
Journal type: peer-reviewed
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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