Successful treatment of human immunodeficiency virus-related Castleman's disease: a case report and literature review (Journal article)

Liberopoulos, E./ Tolis, C./ Bai, M./ Efremidis, S./ Pavlidis, N./ Elisaf, M. S.


Multicentric Castleman's disease is increasingly recognized as an aggressive illness with a rapidly fatal outcome in human immunodeficiency virus (HIV)-infected patients. In the absence of optimal therapy, various therapeutic interventions have been tested with disappointing results; only five reports with a successful outcome have been described. Presented herein is a 66-year-old HIV-infected man with multicentric Castleman's disease. Early administration of cyclophosphamide, doxorubicin, vincristine and prednisone resulted in prolonged clinical recovery. The relevant literature is also reviewed.
Institution and School/Department of submitter: Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Keywords: Aged,Antineoplastic Combined Chemotherapy Protocols/*therapeutic use,Giant Lymph Node Hyperplasia/*drug therapy/*pathology/virology,HIV Infections/*complications,Humans,Immunohistochemistry,Lymph Nodes/pathology,Male,Plasma Cells/pathology,Splenomegaly/radiography/virology,Tomography, X-Ray Computed,Treatment Outcome
URI: http://olympias.lib.uoi.gr/jspui/handle/123456789/18014
ISSN: 0030-2414
Link: http://www.ncbi.nlm.nih.gov/pubmed/12931026
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Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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